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The Extent of Linkage Disequilibrium and Haplotype Sharing Around a Polymorphic Site
https://ir.soken.ac.jp/records/4433
https://ir.soken.ac.jp/records/4433e0708405-0d34-4886-8988-29d6d8173f9e
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2014-04-18 | |||||
タイトル | ||||||
タイトル | The Extent of Linkage Disequilibrium and Haplotype Sharing Around a Polymorphic Site | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The Extent of Linkage Disequilibrium and Haplotype Sharing Around a Polymorphic Site | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
INNAN, Hideki
× INNAN, Hideki× NORDBORG, Magnus |
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著者別名 |
印南, 秀樹
× 印南, 秀樹 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Various expressions related to the length of a conserved haplotype around a polymorphism of known frequency are derived. We obtain exact expressions for the probability that no recombination has occurred in a sample or subsample. We obtain an approximation for the probability that no recombination that could give rise to a detectable recombination event (through the four-gamete test) has occurred. The probabilities can be used to obtain approximate distributions for the length of variously defined haplotypes around a polymorphic site. The implications of our results for data analysis, and in particular for detecting selection, are discussed. | |||||
書誌情報 |
Genetics en : Genetics 巻 165, 号 1, p. 437-444, 発行日 2003-09-01 |
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出版者 | ||||||
出版者 | The Genetics Society of America | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0016-6731 | |||||
権利 | ||||||
権利情報 | © 2003 by The Genetics Society of America | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.genetics.org/content/genetics/165/1/437.full.pdf | |||||
関連名称 | The Genetics Society of America |