{"created":"2023-06-20T13:21:05.113181+00:00","id":1179,"links":{},"metadata":{"_buckets":{"deposit":"bda4d056-a33f-46e4-b3d1-f792930f7ca1"},"_deposit":{"created_by":1,"id":"1179","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"1179"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00001179","sets":["2:430:22"]},"author_link":["0","0","0"],"item_1_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中田, 大貴"}],"nameIdentifiers":[{}]}]},"item_1_creator_3":{"attribute_name":"フリガナ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ナカタ, ヒロキ"}],"nameIdentifiers":[{}]}]},"item_1_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2006-09-29"}]},"item_1_degree_grantor_5":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"総合研究大学院大学"}]}]},"item_1_degree_name_6":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（理学）"}]},"item_1_description_12":{"attribute_name":"要旨","attribute_value_mlt":[{"subitem_description":"The go/nogo task is a useful paradigm for recording event-related
potentials (ERPs) to investigate the neural mechanisms of response
inhibition. In nogo trials, a negative deflection at around 140-300 ms,
which has been called the ‘nogo potentials’ is elicited at the frontocentral
electrodes, compared with ERPs recorded in go trials. In the first study,
we investigated the generators for nogo potentials by recording
magnetoencephalography (MEG) during somatosensory go/nogo tasks.
MEG data revealed that a long-latency response peaking at approximately
160 ms, termed nogo-M170, recorded in only nogo trials. The equivalent
current dipole (ECD) of nogo-M170 was estimated to lie around the
posterior part of the inferior frontal sulci in the prefrontal cortex. This
finding clarified the spatial and temporal processing related to
somato-motor inhibition caused in the posterior part of the inferior frontal
sulci in the prefrontal cortex in humans.
In the second study, we investigated the effect of the inhibitory
processing with increasing muscle force on motor evoked potentials
(MEPs) elicited by transcranial magnetic stimulation (TMS). The
subjects performed a warning stimulus (S1) －imperative stimulus (S2)
paradigm with go/nogo tasks. S1 was an auditory tone burst, and S2 was
an electrical stimulation for the second (go stimuli) or fifth digit (nogo
stimuli) of the left hand at an even probability in go/nogo tasks. The
recordings were conducted at three force levels; 10 %, 30 % and 50 %
maximal voluntary contraction (MVC). After the presentation of S2, the
subjects were asked to adjust their force level so as to match the target line
with a force trajectory line as quickly and accurately as possible in only the
go trials. The amplitude of the MEP, which was recorded from the first
dorsal interosseous (FDI) muscle 150 ms after S2, in nogo trials became
significantly smaller with increasing muscle force, whereas it became
larger in go trials. Our results indicated that stronger inhibitory cerebral
activity was needed for a nogo stimulus, in the case where a stronger
response was needed for a go stimulus.","subitem_description_type":"Other"}]},"item_1_description_18":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_1_description_7":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_description":"総研大甲第1008号","subitem_description_type":"Other"}]},"item_1_select_14":{"attribute_name":"所蔵","attribute_value_mlt":[{"subitem_select_item":"有"}]},"item_1_select_8":{"attribute_name":"研究科","attribute_value_mlt":[{"subitem_select_item":"生命科学研究科"}]},"item_1_select_9":{"attribute_name":"専攻","attribute_value_mlt":[{"subitem_select_item":"20 生理科学専攻"}]},"item_1_text_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_text_value":"2006"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"NAKATA, Hiroki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"simple","filename":"甲1008_要旨.pdf","filesize":[{"value":"343.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"要旨・審査要旨","url":"https://ir.soken.ac.jp/record/1179/files/甲1008_要旨.pdf"},"version_id":"fa09cabd-2b8b-4b8d-a47b-52d3919e2c8d"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"simple","filename":"甲1008_本文.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"本文","url":"https://ir.soken.ac.jp/record/1179/files/甲1008_本文.pdf"},"version_id":"4ac96331-81ca-4d53-b856-d8f465310963"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm"},{"subitem_title":"Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm","subitem_title_language":"en"}]},"item_type_id":"1","owner":"1","path":["22"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-02-22"},"publish_date":"2010-02-22","publish_status":"0","recid":"1179","relation_version_is_last":true,"title":["Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-20T16:08:14.101205+00:00"}