{"created":"2023-06-20T13:21:05.113181+00:00","id":1179,"links":{},"metadata":{"_buckets":{"deposit":"bda4d056-a33f-46e4-b3d1-f792930f7ca1"},"_deposit":{"created_by":1,"id":"1179","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"1179"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00001179","sets":["2:430:22"]},"author_link":["0","0","0"],"item_1_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中田, 大貴"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_3":{"attribute_name":"フリガナ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ナカタ, ヒロキ"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_1_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2006-09-29"}]},"item_1_degree_grantor_5":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"総合研究大学院大学"}]}]},"item_1_degree_name_6":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（理学）"}]},"item_1_description_12":{"attribute_name":"要旨","attribute_value_mlt":[{"subitem_description":"The go/nogo task is a useful paradigm for recording event-related<br />potentials (ERPs) to investigate the neural mechanisms of response<br />inhibition.  In nogo trials, a negative deflection at around 140-300 ms,<br />which has been called the ‘nogo potentials’ is elicited at the frontocentral <br />electrodes, compared with ERPs recorded in go trials.  In the first study, <br />we investigated the generators for nogo potentials by recording <br />magnetoencephalography (MEG) during somatosensory go/nogo tasks.  <br />MEG data revealed that a long-latency response peaking at approximately <br />160 ms, termed nogo-M170, recorded in only nogo trials.  The equivalent <br />current dipole (ECD) of nogo-M170 was estimated to lie around the <br />posterior part of the inferior frontal sulci in the prefrontal cortex.  This <br />finding clarified the spatial and temporal processing related to <br />somato-motor inhibition caused in the posterior part of the inferior frontal <br />sulci in the prefrontal cortex in humans.<br />In the second study, we investigated the effect of the inhibitory <br />processing with increasing muscle force on motor evoked potentials <br />(MEPs) elicited by transcranial magnetic stimulation (TMS).  The <br />subjects performed a warning stimulus (S1) －imperative stimulus (S2) <br />paradigm with go/nogo tasks.  S1 was an auditory tone burst, and S2 was <br />an electrical stimulation for the second (go stimuli) or fifth digit (nogo <br />stimuli) of the left hand at an even probability in go/nogo tasks.  The <br />recordings were conducted at three force levels; 10 %, 30 % and 50 % <br />maximal voluntary contraction (MVC).  After the presentation of S2, the <br />subjects were asked to adjust their force level so as to match the target line <br />with a force trajectory line as quickly and accurately as possible in only the <br />go trials.  The amplitude of the MEP, which was recorded from the first <br />dorsal interosseous (FDI) muscle 150 ms after S2, in nogo trials became <br />significantly smaller with increasing muscle force, whereas it became <br />larger in go trials.  Our results indicated that stronger inhibitory cerebral <br />activity was needed for a nogo stimulus, in the case where a stronger <br />response was needed for a go stimulus.","subitem_description_type":"Other"}]},"item_1_description_18":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_1_description_7":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_description":"総研大甲第1008号","subitem_description_type":"Other"}]},"item_1_select_14":{"attribute_name":"所蔵","attribute_value_mlt":[{"subitem_select_item":"有"}]},"item_1_select_8":{"attribute_name":"研究科","attribute_value_mlt":[{"subitem_select_item":"生命科学研究科"}]},"item_1_select_9":{"attribute_name":"専攻","attribute_value_mlt":[{"subitem_select_item":"20 生理科学専攻"}]},"item_1_text_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_text_value":"2006"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"NAKATA, Hiroki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"0","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"simple","filename":"甲1008_要旨.pdf","filesize":[{"value":"343.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"要旨・審査要旨","url":"https://ir.soken.ac.jp/record/1179/files/甲1008_要旨.pdf"},"version_id":"fa09cabd-2b8b-4b8d-a47b-52d3919e2c8d"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"simple","filename":"甲1008_本文.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"本文","url":"https://ir.soken.ac.jp/record/1179/files/甲1008_本文.pdf"},"version_id":"4ac96331-81ca-4d53-b856-d8f465310963"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm"},{"subitem_title":"Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm","subitem_title_language":"en"}]},"item_type_id":"1","owner":"1","path":["22"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-02-22"},"publish_date":"2010-02-22","publish_status":"0","recid":"1179","relation_version_is_last":true,"title":["Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-20T16:08:14.101205+00:00"}