{"created":"2023-06-20T13:22:33.009150+00:00","id":3204,"links":{},"metadata":{"_buckets":{"deposit":"9ed57369-061f-4c9d-8545-7745c677739f"},"_deposit":{"created_by":21,"id":"3204","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"3204"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00003204","sets":["33:34"]},"author_link":["344","343"],"item_2_creator_3":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"GOJOBORI, Jun","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_2_date_4":{"attribute_name":"発行日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-06-18","subitem_date_issued_type":"Created"}]},"item_2_description_13":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"20870017","subitem_description_type":"Other"}]},"item_2_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_16":{"attribute_name":"研究期間","attribute_value_mlt":[{"subitem_description":"2008～2009","subitem_description_type":"Other"}]},"item_2_description_17":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：ヒト集団は、アフリカ、アジア、ヨーロッパの各集団に別れるが、\r\nそれぞれの集団はそれぞれに異なった環境への適応を果たして来たと考えられる。しかし、\r\nその遺伝的基盤ははっきりと知られていないので、それを知るためにヒトの遺伝病の原因\r\nになる突然変異の情報を用いてヒト集団を比較した。その結果、病気になりやすい突然変\r\n異の分布は各集団で大きな違いが見られず、特にヨーロッパ集団以外の集団の遺伝病のデ\r\nータが必要であることが示唆された。\r\n研究成果の概要（英文）：There are three major populations in humans, Africa, Asia and\r\nEurope. They experienced their own adaptations against environments but the\r\ngenetic background of these adaptations is not well understood. In this study, to\r\nunderstand these genetic backgrounds, I used the data of mutations of human disease\r\nand defined which types of amino acid changes are more likely to cause disease. The\r\ndistributions of these mutations are not different among human populations, which\r\nsuggests that more data other than European are needed.","subitem_description_type":"Abstract"}]},"item_2_description_18":{"attribute_name":"科研費研究者番号","attribute_value_mlt":[{"subitem_description":"00506800 | http://rns.nii.ac.jp/d/nr/1000000506800","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"科学研究費補助金研究成果報告書 \r\n研究代表者：五條堀淳［総合研究大学院大学葉山高等研究センター上級研究員］ ","subitem_description_type":"Other"}]},"item_2_relation_11":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"KAKEN（科学研究費補助金データーベース） "}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://kaken.nii.ac.jp/d/r/00506800.ja.html","subitem_relation_type_select":"URI"}}]},"item_2_text_19":{"attribute_name":"研究分野","attribute_value_mlt":[{"subitem_text_value":"分子進化学、集団遺伝学"}]},"item_2_text_20":{"attribute_name":"研究種目","attribute_value_mlt":[{"subitem_text_value":"若手研究（スタートアップ）"}]},"item_2_text_21":{"attribute_name":"科研費の分科・細目","attribute_value_mlt":[{"subitem_text_value":"生物系、生物学、自然人類学"}]},"item_2_text_5":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_text_value":"2009"}]},"item_2_version_type_12":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"五條堀, 淳"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-10-25"}],"displaytype":"simple","filename":"20870017seika.pdf","filesize":[{"value":"250.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"研究成果報告書","url":"https://ir.soken.ac.jp/record/3204/files/20870017seika.pdf"},"version_id":"afead018-8e18-4d60-9bdf-f910883a3330"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"集団、進化、突然変異、病気、アミノ酸の変化","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"病気からみたヒト集団の遺伝的分化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"病気からみたヒト集団の遺伝的分化"},{"subitem_title":"Diseases and genetic differentiation of human population","subitem_title_language":"en"}]},"item_type_id":"2","owner":"21","path":["34"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-01-01"},"publish_date":"2012-01-01","publish_status":"0","recid":"3204","relation_version_is_last":true,"title":["病気からみたヒト集団の遺伝的分化"],"weko_creator_id":"21","weko_shared_id":-1},"updated":"2023-06-20T15:37:05.773514+00:00"}