{"created":"2023-06-20T13:22:55.344111+00:00","id":3648,"links":{},"metadata":{"_buckets":{"deposit":"5b0fa811-5fb1-4f25-90a0-1eae00359222"},"_deposit":{"created_by":21,"id":"3648","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"3648"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00003648","sets":["1:275"]},"author_link":["1541","341","342"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"1127","bibliographicPageStart":"1122","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"Molecular Biology and Evolution "},{"bibliographic_title":"Molecular Biology and Evolution ","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"印南, 秀樹"}],"nameIdentifiers":[{},{},{}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Awadalla, Eyre-Walker, and Maynard Smith (1999)<$REFLINK> recently argued that there might be recombination in human mitochondrial DNA (mtDNA). Their claim was based on their observation of decaying linkage disequilibrium (LD) as a function of physical distance. Their study was much criticized, and follow-up studies have failed to find any evidence for recombination. We argue that the criticisms levied, even if correct, could not possibly explain the findings of Awadalla, Eyre-Walker, and Maynard Smith (1999)<$REFLINK> . Nonetheless, the test proposed by Awadalla, Eyre-Walker, and Maynard Smith (1999<$REFLINK> ) is not robust because recombination is not the only explanation for decay of LD. We show that such a pattern can be caused by mutational hot spots as well. However, a closer look at the data suggests that the pattern observed was not caused by mutational hot spots but rather by chance. Thus, there appears to be no evidence for recombination in the mtDNA polymorphism data. In conclusion, we discuss the possibility of detecting recombination in mtDNA and the implications of its existence. ","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford University Press"}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"12082131","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1093/oxfordjournals.molbev.a004170"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1093/oxfordjournals.molbev.a004170","subitem_relation_type_select":"DOI"}}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"07374038 ","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"INNAN, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NORDBORG, Magnus "}],"nameIdentifiers":[{}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Recombination or mutational hot spots in human mtDNA?","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Recombination or mutational hot spots in human mtDNA?"},{"subitem_title":"Recombination or mutational hot spots in human mtDNA?","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"21","path":["275"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-06-27"},"publish_date":"2013-06-27","publish_status":"0","recid":"3648","relation_version_is_last":true,"title":["Recombination or mutational hot spots in human mtDNA?"],"weko_creator_id":"21","weko_shared_id":21},"updated":"2023-06-20T14:31:50.260132+00:00"}