{"created":"2023-06-20T13:22:57.762271+00:00","id":3703,"links":{},"metadata":{"_buckets":{"deposit":"e8b4ca45-ce64-4f20-9354-f8975fea6685"},"_deposit":{"created_by":21,"id":"3703","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"3703"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00003703","sets":["1:285","1:314"]},"author_link":["1604","1581","1603","778","357"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"1907","bibliographicPageStart":"1897","bibliographicVolumeNumber":"166","bibliographic_titles":[{"bibliographic_title":"Genetics"},{"bibliographic_title":"Genetics","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"尚之, 高畑"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"New World monkeys (NWMs) occupy a critical phylogenetic position in elucidating the evolutionary process of major histocompatibility complex (MHC) class I genes in primates. From three subfamilies of Aotinae, Cebinae, and Atelinae, the 5′-flanking regions of 18 class I genes are obtained and phylogenetically examined in terms of Alu/LINE insertion elements as well as the nucleotide substitutions. Two pairs of genes from Aotinae and Atelinae are clearly orthologous to human leukocyte antigen (HLA) -E and -F genes. Of the remaining 14 genes, 8 belong to the distinct group B, together with HLA-B and -C, to the exclusion of all other HLA class I genes. These NWM genes are classified into four groups, designated as NWM-B1, -B2, -B3, and -B4. Of these, NWM-B2 is orthologous to HLA-B/C. Also, orthologous relationships of NWM-B1, -B2, and -B3 exist among different families of Cebidae and Atelidae, which is in sharp contrast to the genus-specific gene organization within the subfamily Callitrichinae. The other six genes belong to the distinct group G. However, a clade of these NWM genes is almost equally related to HLA-A, -J, -G, and -K, and there is no evidence for their orthologous relationships to HLA-G. It is argued that class I genes in simian primates duplicated extensively in their common ancestral lineage and that subsequent evolution in descendant species has been facilitated mainly by independent loss of genes. ","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Genetics Society of America "}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"15126407","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1534/genetics.166.4.1897"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1534/genetics.166.4.1897 ","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2004 by The Genetics Society of America"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00166731","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"SAWAI, Hiromi "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KAWAMOTO, Yoshi "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKAHATA, Naoyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SATTA, Yoko"}],"nameIdentifiers":[{}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Evolutionary Relationships of Major Histocompatibility Complex Class I Genes in Simian Primates","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evolutionary Relationships of Major Histocompatibility Complex Class I Genes in Simian Primates"},{"subitem_title":"Evolutionary Relationships of Major Histocompatibility Complex Class I Genes in Simian Primates","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"21","path":["285","314"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-07-03"},"publish_date":"2013-07-03","publish_status":"0","recid":"3703","relation_version_is_last":true,"title":["Evolutionary Relationships of Major Histocompatibility Complex Class I Genes in Simian Primates"],"weko_creator_id":"21","weko_shared_id":21},"updated":"2023-06-20T14:31:11.961237+00:00"}