{"created":"2023-06-20T13:22:57.891474+00:00","id":3705,"links":{},"metadata":{"_buckets":{"deposit":"b0af2dfa-0382-4126-930d-9c1b002dbf55"},"_deposit":{"created_by":21,"id":"3705","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"3705"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00003705","sets":["1:314"]},"author_link":["1577","778"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"595","bibliographicPageStart":"585","bibliographicVolumeNumber":"129","bibliographic_titles":[{"bibliographic_title":"Genetics"},{"bibliographic_title":"Genetics","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"尚之, 高畑"}],"nameIdentifiers":[{},{},{}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In a geographically structured population, the interplay among gene migration, genetic drift and natural selection raises intriguing evolutionary problems, but the rigorous mathematical treatment is often very difficult. Therefore several approximate formulas were developed concerning the coalescence process of neutral genes and the fixation process of selected mutations in an island model, and their accuracy was examined by computer simulation. When migration is limited, the coalescence (or divergence) time for sampled neutral genes can be described by the convolution of exponential functions, as in a panmictic population, but it is determined mainly by migration rate and the number of demes from which the sample is taken. This time can be much longer than that in a panmictic population with the same number of breeding individuals. For a selected mutation, the spreading over the entire population was formulated as a birth and death process, in which the fixation probability within a deme plays a key role. With limited amounts of migration, even advantageous mutations take a large number of generations to spread. Furthermore, it is likely that these mutations which are temporarily fixed in some demes may be swamped out again by non-mutant immigrants from other demes unless selection is strong enough. These results are potentially useful for testing quantitatively various hypotheses that have been proposed for the origin of modern human populations. ","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Genetics Society of America "}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"1743494","subitem_relation_type_select":"PMID"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 1991 by The Genetics Society of America "}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00166731 ","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"TAKAHATA, Naoyuki"}],"nameIdentifiers":[{}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Genealogy of neutral genes and spreading of selected mutations in a geographically structured population","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Genealogy of neutral genes and spreading of selected mutations in a geographically structured population"},{"subitem_title":"Genealogy of neutral genes and spreading of selected mutations in a geographically structured population","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"21","path":["104","314"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-07-03"},"publish_date":"2013-07-03","publish_status":"0","recid":"3705","relation_version_is_last":true,"title":["Genealogy of neutral genes and spreading of selected mutations in a geographically structured population"],"weko_creator_id":"21","weko_shared_id":21},"updated":"2023-06-20T14:15:20.305849+00:00"}