{"created":"2023-06-20T13:22:59.425703+00:00","id":3741,"links":{},"metadata":{"_buckets":{"deposit":"765eb48b-3b21-4085-adcd-544418bab74f"},"_deposit":{"created_by":21,"id":"3741","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"3741"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00003741","sets":["1:314"]},"author_link":["1647","1577","1648","778"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1981-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"8","bibliographicPageStart":"1","bibliographicVolumeNumber":"18","bibliographic_titles":[{"bibliographic_title":"Journal of Molecular Evolution "},{"bibliographic_title":"Journal of Molecular Evolution ","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"尚之, 高畑"}],"nameIdentifiers":[{},{},{}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We develop a mathematical model for estimating evolutionary distance from restriction enzyme maps, which incorporates non-uniformity of the rate of base substitution into the theory and allows for an arbitrary G+C content at equilibrium. When the G+C content differs significantly from 1/2, the traditional model of base changes can introduce a systematic bias which depends upon the base composition of the restriction site. In addition, the accuracy of estimated evolutionary distance depends heavily upon the choice of restriction enzyme in that the expected number of sites is also affected. Monte Carlo experiments are conducted to check the validity of the present theoretical treatment and from which we draw several cautionary notes on estimation. An application is made to the available data on restriction enzyme maps of human mitochondrial DNA where the G+C content is approximately 1/3.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"SpringerLink "}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"6278152","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1007/BF01733204"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://doi.org/10.1007/BF01733204","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"SpringerLink(The original publication is available at www.springerlink.com) "}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00222844 ","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"TATENO, Yoshio "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"AOKI, Kenichi "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKAHATA, Naoyuki"}],"nameIdentifiers":[{}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Estimating evolutionary distance from restriction maps of mitochondrial DNA with arbitrary G+C content","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Estimating evolutionary distance from restriction maps of mitochondrial DNA with arbitrary G+C content"},{"subitem_title":"Estimating evolutionary distance from restriction maps of mitochondrial DNA with arbitrary G+C content","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"21","path":["314"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-07-04"},"publish_date":"2013-07-04","publish_status":"0","recid":"3741","relation_version_is_last":true,"title":["Estimating evolutionary distance from restriction maps of mitochondrial DNA with arbitrary G+C content"],"weko_creator_id":"21","weko_shared_id":21},"updated":"2023-06-20T14:30:51.726816+00:00"}