@article{oai:ir.soken.ac.jp:00003776,
 author = {尚之, 高畑 and KLEIN, Jan and TAKAHATA, Naoyuki and AYALA, Francisco Jose},
 issue = {6},
 journal = {Scientific American, Scientific American},
 month = {},
 note = {Analysis of the major histocompatibility complex locus, which governs the recognition of self by the immune system, reveals two profound surprises concerning the evolution of humans: the immune system is much older than the species that it protects, and the ancestral population must have been large, not small. There were many Adams and Eves.},
 pages = {78--83+4},
 title = {MHC polymorphism and human origins},
 volume = {269},
 year = {1993}
}