@article{oai:ir.soken.ac.jp:00003987,
 author = {田辺, 秀之 and MäKI-PAAKKANEN, Jorma and HAYASHI, Makoto and SUZUKI, Takayoshi and TANABE, Hideyuki and HONMA, Masamitsu and SOFUNI, Toshio},
 issue = {6},
 journal = {Mutagenesis, Mutagenesis},
 month = {Nov},
 note = {The presence of centromeric DNA was studied in micronuclei isolated from the blood of male ddY mic after five weekly intraperitoneal injections of mitomycu C (MMC), 1-β-D-arabinofuranosylcytosine (Ara-C), colchi cine (COL) or vinblastine sulfate (VBL). In agreement with our earlier findings, about half of the micronuclei isolate* from vehicle control mice showed centromere signals a analyzed by fluorescence in situ hybridization (FISH) with a mouse major (gamma) satellite DNA probe. In an earlie experiment with mice acutely exposed to the same chem icals, the clastogens MMC and Ara-C did not reduce thi proportion of micronuclei with centromere signals. In the present study, however, MMC and Ara-C decreased the proportion of micronuclei with centromeres. In contrast the spindle poisons COL and VBL increased the proportion of micronuclei that contained centromeres.},
 pages = {513--516},
 title = {Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons},
 volume = {10},
 year = {1995}
}