{"created":"2023-06-20T13:23:12.706845+00:00","id":3987,"links":{},"metadata":{"_buckets":{"deposit":"52d82a83-b4ff-4281-988f-4a87864a300c"},"_deposit":{"created_by":21,"id":"3987","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"3987"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00003987","sets":["1:293"]},"author_link":["2144","2109","368","2132","2145","367","2108"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"516","bibliographicPageStart":"513","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Mutagenesis"},{"bibliographic_title":"Mutagenesis","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田辺, 秀之"}],"nameIdentifiers":[{},{},{}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The presence of centromeric DNA was studied in micronuclei isolated from the blood of male ddY mic after five weekly intraperitoneal injections of mitomycu C (MMC), 1-β-D-arabinofuranosylcytosine (Ara-C), colchi cine (COL) or vinblastine sulfate (VBL). In agreement with our earlier findings, about half of the micronuclei isolate* from vehicle control mice showed centromere signals a analyzed by fluorescence in situ hybridization (FISH) with a mouse major (gamma) satellite DNA probe. In an earlie experiment with mice acutely exposed to the same chem icals, the clastogens MMC and Ara-C did not reduce thi proportion of micronuclei with centromere signals. In the present study, however, MMC and Ara-C decreased the proportion of micronuclei with centromeres. In contrast the spindle poisons COL and VBL increased the proportion of micronuclei that contained centromeres. ","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford University Press"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1093/mutage/10.6.513"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1093/mutage/10.6.513","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© Oxford University Press"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0267-8357","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MäKI-PAAKKANEN, Jorma "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HAYASHI, Makoto "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SUZUKI, Takayoshi "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TANABE, Hideyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HONMA, Masamitsu "}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SOFUNI, Toshio "}],"nameIdentifiers":[{}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons"},{"subitem_title":"Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"21","path":["293"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-09-25"},"publish_date":"2013-09-25","publish_status":"0","recid":"3987","relation_version_is_last":true,"title":["Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons"],"weko_creator_id":"21","weko_shared_id":21},"updated":"2023-06-20T14:28:09.681995+00:00"}