{"created":"2023-06-20T13:23:15.459651+00:00","id":4039,"links":{},"metadata":{"_buckets":{"deposit":"7b7673b9-12fd-49f3-872f-ed65192776f9"},"_deposit":{"created_by":21,"id":"4039","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"4039"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00004039","sets":["1:276","1:285","1:314"]},"author_link":["1543","819","1660","774","1662","778","357","1577","2181"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Article ID 917678","bibliographicPageStart":"11","bibliographic_titles":[{"bibliographic_title":"International Journal of Evolutionary Biology"},{"bibliographic_title":"International Journal of Evolutionary Biology","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"尚之, 高畑"}],"nameIdentifiers":[{"nameIdentifier":"1577","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000030124217","nameIdentifierScheme":"NRID","nameIdentifierURI":" "},{"nameIdentifier":"30124217","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30124217"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report the results of an extensive investigation of genomic structures in the human genome, with a particular focus on relatively large repeats (>50 kb) in adjacent chromosomal regions. We named such structures “Flowers” because the pattern observed on dot plots resembles a flower. We detected a total of 291 Flowers in the human genome. They were predominantly located in euchromatic regions. Flowers are gene-rich compared to the average gene density of the genome. Genes involved in systems receiving environmental information, such as immunity and detoxification, were overrepresented in Flowers. Within a Flower, the mean number of duplication units was approximately four. The maximum and minimum identities between homologs in a Flower showed different distributions; the maximum identity was often concentrated to 100% identity, while the minimum identity was evenly distributed in the range of 78% to 100%. Using a gene conversion detection test, we found frequent and/or recent gene conversion events within the tested Flowers. Interestingly, many of those converted regions contained protein-coding genes. Computer simulation studies suggest that one role of such frequent gene conversions is the elongation of the life span of gene families in a Flower by the resurrection of pseudogenes.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Hindawi Publishing Corporation"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1155/2012/917678"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://dx.doi.org/10.1155/2012/917678","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Copyright"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.hindawi.com/journals/apm/apc/","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2012 Hie Lim Kim et al."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2090-052X","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KIM, Hie Lim "}],"nameIdentifiers":[{"nameIdentifier":"1662","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"IWASE, Mineyo"}],"nameIdentifiers":[{"nameIdentifier":"774","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"IGAWA, Takeshi"}],"nameIdentifiers":[{"nameIdentifier":"1660","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"NISHIOKA, Tasuku "}],"nameIdentifiers":[{"nameIdentifier":"2181","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KANEKO, Satoko"}],"nameIdentifiers":[{"nameIdentifier":"1543","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KATSURA, Yukako"}],"nameIdentifiers":[{"nameIdentifier":"819","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TAKAHATA, Naoyuki"}],"nameIdentifiers":[{"nameIdentifier":"778","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SATTA, Yoko"}],"nameIdentifiers":[{"nameIdentifier":"357","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-10-25"}],"displaytype":"simple","filename":"917678[1].pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"917678[1]","url":"https://ir.soken.ac.jp/record/4039/files/917678[1].pdf"},"version_id":"80e343ce-84f6-4672-a113-ab259c0e121b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Genomic structure and evolution of multigene families: “Flowers” on the human genome","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Genomic structure and evolution of multigene families: “Flowers” on the human genome"},{"subitem_title":"Genomic structure and evolution of multigene families: “Flowers” on the human genome","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"21","path":["276","285","314"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-10-25"},"publish_date":"2013-10-25","publish_status":"0","recid":"4039","relation_version_is_last":true,"title":["Genomic structure and evolution of multigene families: “Flowers” on the human genome"],"weko_creator_id":"21","weko_shared_id":21},"updated":"2023-06-20T14:27:40.503806+00:00"}