{"created":"2023-06-20T13:23:22.233052+00:00","id":4188,"links":{},"metadata":{"_buckets":{"deposit":"efac79cc-ce37-436f-8c40-b389006f6a27"},"_deposit":{"created_by":21,"id":"4188","owners":[21],"pid":{"revision_id":0,"type":"depid","value":"4188"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00004188","sets":["1:267","1:448:294"]},"author_link":["660","421","637","1522"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"2445","bibliographicPageStart":"2436","bibliographicVolumeNumber":"270","bibliographic_titles":[{"bibliographic_title":"European Journal of Biochemistry"},{"bibliographic_title":"European Journal of Biochemistry","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"若桑, 基博"}],"nameIdentifiers":[{"nameIdentifier":"1522","nameIdentifierScheme":"WEKO"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Retinoid-binding proteins are indispensable for visual cycles in both vertebrate and invertebrate retinas. These proteins stabilize and transport hydrophobic retinoids in the hydrophilic environment of plasma and cytoplasm, and allow regeneration of visual pigments. Here, we identified a novel retinol-binding protein in the eye of a butterfly, Papilio xuthus. The protein that we term Papilio retinol-binding protein (Papilio RBP) is a major component of retinal soluble proteins and exclusively binds 3-hydroxyretinol, and emits fluorescence peaking at 480 nm under ultraviolet (UV) illumination. The primary structure, deduced from the nucleotide sequence of the cDNA, shows no similarity to any other lipophilic ligand-binding proteins. The molecular mass and isoelectric point of the protein estimated from the amino-acid sequence are 26.4 kDa and 4.92, respectively. The absence of any signal sequence for secretion in the N-terminus suggests that the protein exists in the cytoplasmic matrix. All-trans 3-hydroxyretinol is the major ligand of the Papilio RBP in dark-adapted eyes. Light illumination of the eyes increases the 11-cis isomer of the ligand and induces redistribution of the Papilio RBP from the proximal to the distal part of the photoreceptor layer. These results suggest that the Papilio RBP is involved in visual pigment turnover.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley-Blackwell"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1046/j.1432-1033.2003.03614.x"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":" https://doi.org/10.1046/j.1432-1033.2003.03614.x","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© FEBS 2003"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0014-2956","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"WAKAKUWA, Motohiro"}],"nameIdentifiers":[{"nameIdentifier":"637","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ARIKAWA, Kentaro"}],"nameIdentifiers":[{"nameIdentifier":"421","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"OZAKI, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"660","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus"},{"subitem_title":"A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"21","path":["96","267","294","332"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-01-24"},"publish_date":"2014-01-24","publish_status":"0","recid":"4188","relation_version_is_last":true,"title":["A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus"],"weko_creator_id":"21","weko_shared_id":21},"updated":"2023-06-20T14:26:56.030012+00:00"}