{"created":"2023-06-20T13:24:14.881361+00:00","id":5642,"links":{},"metadata":{"_buckets":{"deposit":"e6f2cbf0-2474-4ae4-b43a-0ad297486ee8"},"_deposit":{"created_by":24,"id":"5642","owners":[24],"pid":{"revision_id":0,"type":"depid","value":"5642"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00005642","sets":["33:34"]},"author_link":["8166","8165"],"item_2_creator_3":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"GOJOBORI, Jun","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_2_date_4":{"attribute_name":"発行日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2013-05-28","subitem_date_issued_type":"Created"}]},"item_2_description_13":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"22770239","subitem_description_type":"Other"}]},"item_2_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_16":{"attribute_name":"研究期間","attribute_value_mlt":[{"subitem_description":"2010～2012","subitem_description_type":"Other"}]},"item_2_description_17":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：\nコーディング領域トリプレットリピートはタンパク質の構造中、不確定領域を形成する事が知られ、そのような領域は進化速度が速いと言われていた。本研究でトリプレットリピートの進化とタンパク質の構造の関連を調べた結果、霊長類における進化では、これまで言われていた事とは逆の、不確定領域になりにくいトリプレットリピートの進化速度が速い事が示され、霊長類特異的な進化の特徴が明らかにされた。\n研究成果の概要（英文）：\nIt is proposed that triplet repeats in coding regions are more likely to form disordered region in protein structure. It is suggested that disordered regions evolve faster. In this study, I examine the relationship between the evolutionary rate and protein structure for triplet repeats in coding regions. I showed that the repeats in non-disordered region evolved faster than disordered region during primate evolution. Here I revealed primate specific evolution on coding triplet repeats.","subitem_description_type":"Abstract"}]},"item_2_description_18":{"attribute_name":"科研費研究者番号","attribute_value_mlt":[{"subitem_description":"00506800 | https://kaken.nii.ac.jp/ja/search/?qm=00506800","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"科学研究費補助金研究成果報告書\n研究代表者：五條堀 淳［総合研究大学院大学先導科学研究科助教］ ","subitem_description_type":"Other"}]},"item_2_relation_11":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"KAKEN（科学研究費補助金データーベース）"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22770239/","subitem_relation_type_select":"URI"}}]},"item_2_text_19":{"attribute_name":"研究分野","attribute_value_mlt":[{"subitem_text_value":"分子進化学、自然人類学"}]},"item_2_text_20":{"attribute_name":"研究種目","attribute_value_mlt":[{"subitem_text_value":"若手研究(B) "}]},"item_2_text_21":{"attribute_name":"科研費の分科・細目","attribute_value_mlt":[{"subitem_text_value":"生物系・生物学・自然人類学"}]},"item_2_text_5":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_text_value":"2013"}]},"item_2_version_type_12":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"五條堀, 淳"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-08"}],"displaytype":"simple","filename":"22770239seika_gojobori.pdf","filesize":[{"value":"312.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"研究成果報告書","url":"https://ir.soken.ac.jp/record/5642/files/22770239seika_gojobori.pdf"},"version_id":"452f72b8-30b9-4f3a-a59e-d2fba1a80b43"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"アミノ酸リピート","subitem_subject_scheme":"Other"},{"subitem_subject":"不確定領域","subitem_subject_scheme":"Other"},{"subitem_subject":"トリプレットリピート","subitem_subject_scheme":"Other"},{"subitem_subject":"進化","subitem_subject_scheme":"Other"},{"subitem_subject":"機能的制約","subitem_subject_scheme":"Other"},{"subitem_subject":"人類学","subitem_subject_scheme":"Other"},{"subitem_subject":"ゲノム","subitem_subject_scheme":"Other"},{"subitem_subject":"脊椎動物","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ヒトのコーディング領域トリプレットリピートの進化的意義","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒトのコーディング領域トリプレットリピートの進化的意義"},{"subitem_title":"The evolution of coding triplet repeats in human genome","subitem_title_language":"en"}]},"item_type_id":"2","owner":"24","path":["34"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-08"},"publish_date":"2017-12-08","publish_status":"0","recid":"5642","relation_version_is_last":true,"title":["ヒトのコーディング領域トリプレットリピートの進化的意義"],"weko_creator_id":"24","weko_shared_id":-1},"updated":"2023-06-20T14:56:14.202069+00:00"}