{"created":"2023-06-20T13:24:15.320189+00:00","id":5652,"links":{},"metadata":{"_buckets":{"deposit":"d0e68101-1f17-4f33-ba42-b99090e77890"},"_deposit":{"created_by":24,"id":"5652","owners":[24],"pid":{"revision_id":0,"type":"depid","value":"5652"},"status":"published"},"_oai":{"id":"oai:ir.soken.ac.jp:00005652","sets":["33:34"]},"author_link":["8200","8201"],"item_2_creator_3":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"INNAN, Hideki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_2_date_4":{"attribute_name":"発行日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2016-06-12","subitem_date_issued_type":"Created"}]},"item_2_description_13":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"23114004","subitem_description_type":"Other"}]},"item_2_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_16":{"attribute_name":"研究期間","attribute_value_mlt":[{"subitem_description":"2011~2015","subitem_description_type":"Other"}]},"item_2_description_17":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要(和文):\n本研究は、真核生物の大部分を占める非コード領域におけるゲノム進化のメカニズムを解明するものである。集団遺伝学および分子進化学の理論を構築するとともに、それらを多種多様なゲノムに適用した。研究対象になった種は、分裂酵母、イネ、ヒトなどの霊長類、シロイヌナズナなどの植物を含む。これらの研究から、非コード領域には非常に強い淘汰にさらされている領域が多数存在することがわかった。これは、非コード領域も細胞を維持する上で重要な役割を担っていることを示唆している。\n研究成果の概要(英文):\nThis research project was aimed to understand the evolutionary mechanisms in noncoding DNA regions, which constitute the majority of the eukaryote genomes. We have carried out theoretical works on population genetics and molecular evolution specifically for noncoding regions, where mutational mechanisms are generally more complex than coding regions. The theory was applied to genomic data from various species including Schizosaccharomyces pombe, rice, human, Arabidopsis thaliana. We found that various modes of natural selection has shaped the current pattern of genome variation within and between species. It was also found that there are a number of noncoding regions that are under strong purifying selection, indicating crucial roles of noncoding regions.","subitem_description_type":"Abstract"}]},"item_2_description_18":{"attribute_name":"科研費研究者番号","attribute_value_mlt":[{"subitem_description":"90444140 | https://kaken.nii.ac.jp/ja/search/?qm=90444140","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"科学研究費補助金研究成果報告書 \n研究代表者:印南 秀樹[総合研究大学院大学その他の研究科准教授] ","subitem_description_type":"Other"}]},"item_2_relation_11":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"KAKEN(科学研究費補助金データーベース)"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PLANNED-23114004/","subitem_relation_type_select":"URI"}}]},"item_2_text_19":{"attribute_name":"研究分野","attribute_value_mlt":[{"subitem_text_value":"集団遺伝"}]},"item_2_text_20":{"attribute_name":"研究種目","attribute_value_mlt":[{"subitem_text_value":"新学術領域研究(研究領域提案型) "}]},"item_2_text_5":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_text_value":"2016"}]},"item_2_version_type_12":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"印南, 秀樹"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-08"}],"displaytype":"simple","filename":"23114004seika_innan.pdf","filesize":[{"value":"174.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"研究成果報告書","url":"https://ir.soken.ac.jp/record/5652/files/23114004seika_innan.pdf"},"version_id":"789bdec2-82fa-471f-82df-36724e4f88d8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"集団遺伝","subitem_subject_scheme":"Other"},{"subitem_subject":"ゲノム進化","subitem_subject_scheme":"Other"},{"subitem_subject":"非コード領域","subitem_subject_scheme":"Other"},{"subitem_subject":"進化","subitem_subject_scheme":"Other"},{"subitem_subject":"ゲノム","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"集団遺伝学理論と比較ゲノムによる非コードDNA領域の進化メカニズム","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"集団遺伝学理論と比較ゲノムによる非コードDNA領域の進化メカニズム"},{"subitem_title":"Population genetic theory and comparative genomics to understand the evolutionary mechanism in noncoding DNA","subitem_title_language":"en"}]},"item_type_id":"2","owner":"24","path":["34"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-08"},"publish_date":"2017-12-08","publish_status":"0","recid":"5652","relation_version_is_last":true,"title":["集団遺伝学理論と比較ゲノムによる非コードDNA領域の進化メカニズム"],"weko_creator_id":"24","weko_shared_id":-1},"updated":"2023-06-20T14:56:18.305516+00:00"}