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A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus
https://ir.soken.ac.jp/records/4188
https://ir.soken.ac.jp/records/41887c46c935-8208-4591-8025-8295510f4340
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2014-01-24 | |||||||||||
| タイトル | ||||||||||||
| タイトル | A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus | |||||||||||
| タイトル | ||||||||||||
| タイトル | A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | metadata only access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||||
| 著者 |
WAKAKUWA, Motohiro
× WAKAKUWA, Motohiro
× ARIKAWA, Kentaro
× OZAKI, Koichi
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| 著者別名 |
若桑, 基博
× 若桑, 基博
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Retinoid-binding proteins are indispensable for visual cycles in both vertebrate and invertebrate retinas. These proteins stabilize and transport hydrophobic retinoids in the hydrophilic environment of plasma and cytoplasm, and allow regeneration of visual pigments. Here, we identified a novel retinol-binding protein in the eye of a butterfly, Papilio xuthus. The protein that we term Papilio retinol-binding protein (Papilio RBP) is a major component of retinal soluble proteins and exclusively binds 3-hydroxyretinol, and emits fluorescence peaking at 480 nm under ultraviolet (UV) illumination. The primary structure, deduced from the nucleotide sequence of the cDNA, shows no similarity to any other lipophilic ligand-binding proteins. The molecular mass and isoelectric point of the protein estimated from the amino-acid sequence are 26.4 kDa and 4.92, respectively. The absence of any signal sequence for secretion in the N-terminus suggests that the protein exists in the cytoplasmic matrix. All-trans 3-hydroxyretinol is the major ligand of the Papilio RBP in dark-adapted eyes. Light illumination of the eyes increases the 11-cis isomer of the ligand and induces redistribution of the Papilio RBP from the proximal to the distal part of the photoreceptor layer. These results suggest that the Papilio RBP is involved in visual pigment turnover. | |||||||||||
| 書誌情報 |
European Journal of Biochemistry en : European Journal of Biochemistry 巻 270, 号 11, p. 2436-2445, 発行日 2003-06 |
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| 出版者 | ||||||||||||
| 出版者 | Wiley-Blackwell | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0014-2956 | |||||||||||
| DOI | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.1046/j.1432-1033.2003.03614.x | |||||||||||
| 関連名称 | 10.1046/j.1432-1033.2003.03614.x | |||||||||||
| 権利 | ||||||||||||
| 権利情報 | © FEBS 2003 | |||||||||||
