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  1. 020 学位論文
  2. 生命科学研究科
  3. 20 生理科学専攻

Effects of local nicotinic activatioon of the superior colliculus on saccades in monkeys

https://ir.soken.ac.jp/records/1152
https://ir.soken.ac.jp/records/1152
d87e4bf0-ec85-48c9-96e7-1ddeabb2e935
名前 / ファイル ライセンス アクション
甲817_要旨.pdf 要旨・審査要旨 / Abstract, Screening Result (169.5 kB)
甲817_本文.pdf 本文 (4.9 MB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2010-02-22
タイトル
タイトル Effects of local nicotinic activatioon of the superior colliculus on saccades in monkeys
タイトル
タイトル Effects of local nicotinic activatioon of the superior colliculus on saccades in monkeys
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_46ec
資源タイプ thesis
著者名 渡邊, 雅之

× 渡邊, 雅之

渡邊, 雅之

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フリガナ ワタナベ, マサユキ

× ワタナベ, マサユキ

ワタナベ, マサユキ

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著者 WATANABE, Masayuki

× WATANABE, Masayuki

en WATANABE, Masayuki

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学位授与機関
学位授与機関名 総合研究大学院大学
学位名
学位名 博士(理学)
学位記番号
内容記述タイプ Other
内容記述 総研大甲第817号
研究科
値 生命科学研究科
専攻
値 20 生理科学専攻
学位授与年月日
学位授与年月日 2004-09-30
学位授与年度
値 2004
要旨
内容記述タイプ Other
内容記述 To examine the role of competitive and cooperative neural interactions within the intermediate layer of superior colliculus (SC), they elevated the basal SC neuronal activity by locally injecting a cholinergic agonist nicotine and analyzed its effects on saccade performance. After microinjection, spontaneous saccades were directed toward the movement field of neurons at the injection site (affected area). For visually guided saccades, reaction times were decreased when targets were presented close to the affected area. However, when visual targets were presented remote from the affected area, reaction times were not increased regardless of the rostro-caudal level of the injection sites. The endpoints of visually guided saccades were biased toward the affected area when targets were presented close to the affected area. After this endpoint effect diminished, the trajectories of visually guided saccades remained modestly curved toward the affected area. Compared to the effects on endpoints, the effects on reaction times were more localized to the targets close to the affected area. These results are consistent with a model that saccades are triggered by the activities of neurons within a restricted region and the endpoints and trajectories of the saccades are determined by the widespread population activity in the SC. However, because increased reaction times were not observed for saccades toward targets remote from the affected area, inhibitory interactions in the SC may not be strong enough to shape the spatial distribution of the low-frequency preparatory activities in the SC.
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内容記述タイプ Other
内容記述 application/pdf
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