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Asymmetric control mechanisms of bimanual coordination: an application of directed connectivity analysis to kinematic and functional MRI data
https://ir.soken.ac.jp/records/1198
https://ir.soken.ac.jp/records/119872dbb73d-d8db-4aca-ad0e-12c6cfd1d41c
| 名前 / ファイル | ライセンス | アクション |
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要旨・審査要旨 (309.8 kB)
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本文 (1.2 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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| 公開日 | 2010-02-22 | |||||
| タイトル | ||||||
| タイトル | Asymmetric control mechanisms of bimanual coordination: an application of directed connectivity analysis to kinematic and functional MRI data | |||||
| タイトル | ||||||
| タイトル | Asymmetric control mechanisms of bimanual coordination: an application of directed connectivity analysis to kinematic and functional MRI data | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
| 資源タイプ | thesis | |||||
| 著者名 |
牧, 陽子
× 牧, 陽子 |
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| フリガナ |
マキ, ヨウコ
× マキ, ヨウコ |
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| 著者 |
MAKI, Yoko
× MAKI, Yoko |
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| 学位授与機関 | ||||||
| 学位授与機関名 | 総合研究大学院大学 | |||||
| 学位名 | ||||||
| 学位名 | 博士（理学） | |||||
| 学位記番号 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 総研大甲第1205号 | |||||
| 研究科 | ||||||
| 値 | 生命科学研究科 | |||||
| 専攻 | ||||||
| 値 | 20 生理科学専攻 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2008-09-30 | |||||
| 学位授与年度 | ||||||
| 値 | 2008 | |||||
| 要旨 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Mirror-symmetrical bimanual movement is more stable than parallel<br />bimanual movement. This is well established at the kinematic level. I used functional<br />MRI (fMRI) to evaluate the neural substrates of the stability of mirror-symmetrical<br />bimanual movement. Right-handed participants (<i>n</i>= 17) rotated disks with their<br />index fingers bimanually, both in mirror-symmetrical and asymmetrical parallel<br />modes. I applied the Akaike causality model to both kinematic and fMRI time-series<br />data. I hypothesized that kinematic stability is represented by the extent of neural<br />"cross-talk": as the fraction of signals that are common to controlling both hands<br />increases, the stability also increases. The standard deviation of the phase difference<br />for the mirror mode was significantly smaller than that for the parallel mode, <br />confirming that the former was more stable. I used the noise-contribution ratio<br />(NCR), which was computed using a multivariate autoregressive model with latent<br />variables, as a direct measure of the cross-talk between both the two hands and the<br />bilateral primary motor cortices (M ls).The mode-by-direction interaction of the<br />NCR was significant in both the kinematic and fMRI data. Furthermore, in both sets<br />of data, the NCR from the right hand to the left was more prominent than vice versa<br />during the mirror-symmetrical mode, whereas no difference was observed during<br />parallel movement or rest. The asymmetric interhemispheric interaction from the left<br />M l to the right M l during symmetric bimanual movement might represent<br />cortical-level cross-talk, which contributes to the stability of symmetric bimanual<br />movements. | |||||
| 所蔵 | ||||||
| 値 | 有 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
