| Item type |
学位論文 / Thesis or Dissertation(1) |
| 公開日 |
2010-02-22 |
| タイトル |
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|
タイトル |
Asymmetric control mechanisms of bimanual coordination: an application of directed connectivity analysis to kinematic and functional MRI data |
| タイトル |
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タイトル |
Asymmetric control mechanisms of bimanual coordination: an application of directed connectivity analysis to kinematic and functional MRI data |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_46ec |
|
資源タイプ |
thesis |
| 著者名 |
牧, 陽子
|
| フリガナ |
マキ, ヨウコ
|
| 著者 |
MAKI, Yoko
|
| 学位授与機関 |
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学位授与機関名 |
総合研究大学院大学 |
| 学位名 |
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学位名 |
博士（理学） |
| 学位記番号 |
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内容記述タイプ |
Other |
|
内容記述 |
総研大甲第1205号 |
| 研究科 |
|
|
値 |
生命科学研究科 |
| 専攻 |
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|
値 |
20 生理科学専攻 |
| 学位授与年月日 |
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学位授与年月日 |
2008-09-30 |
| 学位授与年度 |
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|
2008 |
| 要旨 |
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内容記述タイプ |
Other |
|
内容記述 |
Mirror-symmetrical bimanual movement is more stable than parallel<br />bimanual movement. This is well established at the kinematic level. I used functional<br />MRI (fMRI) to evaluate the neural substrates of the stability of mirror-symmetrical<br />bimanual movement. Right-handed participants (<i>n</i>= 17) rotated disks with their<br />index fingers bimanually, both in mirror-symmetrical and asymmetrical parallel<br />modes. I applied the Akaike causality model to both kinematic and fMRI time-series<br />data. I hypothesized that kinematic stability is represented by the extent of neural<br />"cross-talk": as the fraction of signals that are common to controlling both hands<br />increases, the stability also increases. The standard deviation of the phase difference<br />for the mirror mode was significantly smaller than that for the parallel mode, <br />confirming that the former was more stable. I used the noise-contribution ratio<br />(NCR), which was computed using a multivariate autoregressive model with latent<br />variables, as a direct measure of the cross-talk between both the two hands and the<br />bilateral primary motor cortices (M ls).The mode-by-direction interaction of the<br />NCR was significant in both the kinematic and fMRI data. Furthermore, in both sets<br />of data, the NCR from the right hand to the left was more prominent than vice versa<br />during the mirror-symmetrical mode, whereas no difference was observed during<br />parallel movement or rest. The asymmetric interhemispheric interaction from the left<br />M l to the right M l during symmetric bimanual movement might represent<br />cortical-level cross-talk, which contributes to the stability of symmetric bimanual<br />movements. |
| 所蔵 |
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値 |
有 |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
要旨・審査要旨 (309.8 kB)
