Item type |
学位論文 / Thesis or Dissertation(1) |
公開日 |
2010-03-24 |
タイトル |
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タイトル |
A Study for Development of Close-to-Physiological State Imaging Methods |
タイトル |
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タイトル |
A Study for Development of Close-to-Physiological State Imaging Methods |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_46ec |
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資源タイプ |
thesis |
著者名 |
福田, 善之
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フリガナ |
フクダ, ヨシユキ
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著者 |
FUKUDA, Yoshiyuki
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学位授与機関 |
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学位授与機関名 |
総合研究大学院大学 |
学位名 |
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学位名 |
博士(理学) |
学位記番号 |
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内容記述タイプ |
Other |
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内容記述 |
総研大甲第1257号 |
研究科 |
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値 |
生命科学研究科 |
専攻 |
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値 |
20 生理科学専攻 |
学位授与年月日 |
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学位授与年月日 |
2009-03-24 |
学位授与年度 |
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値 |
2008 |
要旨 |
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内容記述タイプ |
Other |
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内容記述 |
In the field of neuroscience, low-invasive <i>in vivo</i> imaging would be a very<br /> useful method of monitoring the morphological dynamics of intact neurons in living<br /> animals. At present, there are two widely used <i>in vivo</i> imaging methods; one is the<br />two-photon microscope method, and the other is the fiber optics method. However,<br />these methods are not suitable for the <i>in vivo</i> imaging of deeper subcortical structures.<br /> In this study, a novel method for the <i>in vivo</i> imaging of pyramidal neurons in layer V of<br />the cerebral cortex has developed by utilizing a MicroLSM system and a stick-type<br /> objective lens that can be directly inserted into the target tissue. By using this method,<br />clear images of pyramidal neurons in layer V of the cerebral cortex were successfully<br />obtained under a low-invasive condition. The MicroLSM system is a useful and<br /> versatile <i>in vivo</i> imaging system that will be applicable not only to<br /> the brain but also to other organs. |
所蔵 |
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値 |
有 |