| Item type |
学位論文 / Thesis or Dissertation(1) |
| 公開日 |
2010-03-24 |
| タイトル |
|
|
タイトル |
A Study for Development of Close-to-Physiological State Imaging Methods |
| タイトル |
|
|
タイトル |
A Study for Development of Close-to-Physiological State Imaging Methods |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_46ec |
|
資源タイプ |
thesis |
| 著者名 |
福田, 善之
|
| フリガナ |
フクダ, ヨシユキ
|
| 著者 |
FUKUDA, Yoshiyuki
|
| 学位授与機関 |
|
|
|
学位授与機関名 |
総合研究大学院大学 |
| 学位名 |
|
|
学位名 |
博士（理学） |
| 学位記番号 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
総研大甲第1257号 |
| 研究科 |
|
|
値 |
生命科学研究科 |
| 専攻 |
|
|
値 |
20 生理科学専攻 |
| 学位授与年月日 |
|
|
学位授与年月日 |
2009-03-24 |
| 学位授与年度 |
|
|
値 |
2008 |
| 要旨 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
In the field of neuroscience, low-invasive <i>in vivo</i> imaging would be a very<br /> useful method of monitoring the morphological dynamics of intact neurons in living<br /> animals. At present, there are two widely used <i>in vivo</i> imaging methods; one is the<br />two-photon microscope method, and the other is the fiber optics method. However,<br />these methods are not suitable for the <i>in vivo</i> imaging of deeper subcortical structures.<br /> In this study, a novel method for the <i>in vivo</i> imaging of pyramidal neurons in layer V of<br />the cerebral cortex has developed by utilizing a MicroLSM system and a stick-type<br /> objective lens that can be directly inserted into the target tissue. By using this method,<br />clear images of pyramidal neurons in layer V of the cerebral cortex were successfully<br />obtained under a low-invasive condition. The MicroLSM system is a useful and<br /> versatile <i>in vivo</i> imaging system that will be applicable not only to<br /> the brain but also to other organs. |
| 所蔵 |
|
|
値 |
有 |
要旨・審査要旨 (389.3 kB)
