WEKO3
アイテム
No Evidence for a Second Evolutionary Stratum during the Early Evolution of Mammalian Sex Chromosomes
https://ir.soken.ac.jp/records/3324
https://ir.soken.ac.jp/records/332457150b76-f937-40b3-83a9-413e8507e5f3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
fetchObject (1.1 MB)
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2013-01-17 | |||||||||
| タイトル | ||||||||||
| タイトル | No Evidence for a Second Evolutionary Stratum during the Early Evolution of Mammalian Sex Chromosomes | |||||||||
| タイトル | ||||||||||
| タイトル | No Evidence for a Second Evolutionary Stratum during the Early Evolution of Mammalian Sex Chromosomes | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
KATSURA, Yukako
× KATSURA, Yukako
× SATTA, Yoko
|
|||||||||
| 著者別名 |
颯田, 葉子
× 颯田, 葉子
|
|||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Mammalian sex chromosomes originated from a pair of autosomes, and homologous genes on the sex chromosomes (gametologs) differentiated through recombination arrest between the chromosomes. It was hypothesized that this differentiation in eutherians took place in a stepwise fashion and left a footprint on the X chromosome termed “evolutionary strata.” The evolutionary stratum hypothesis claims that strata 1 and 2 (which correspond to the first two steps of chromosomal differentiation) were generated in the stem lineage of Theria or before the divergence between eutherians and marsupials. However, this prediction relied solely on the molecular clock hypothesis between pairs of human gametologs, and molecular evolution of marsupial sex chromosomal genes has not yet been investigated. In this study, we analyzed the following 7 pairs of marsupial gametologs, together with their eutherian orthologs that reside in stratum 1 or 2: SOX3/SRY, RBMX/Y, RPS4X/Y, HSFX/Y, XKRX/Y, SMCX/Y (KDM5C/D, JARID1C/D), and UBE1X/Y (UBA1/UBA1Y). Phylogenetic analyses and estimated divergence time of these gametologs reveal that they all differentiated at the same time in the therian ancestor. We have also provided strong evidence for gene conversion that occurred in the 3′ region of the eutherian stratum 2 genes (SMCX/Y and UBE1X/Y). The results of the present study show that (1) there is no compelling evidence for the second stratum in the stem lineage of Theria; (2) gene conversion, which may have occurred between SMCX/Y and UBE1X/Y in the eutherian lineage, potentially accounts for their apparently lower degree of overall divergence. | |||||||||
| 書誌情報 |
PLoS ONE en : PLoS ONE 巻 7, 号 10, 発行日 2012-10-19 |
|||||||||
| 出版者 | ||||||||||
| 出版者 | Public Library of Science | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 19326203 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1371/journal.pone.0097169 | |||||||||
| 関連名称 | 10.1371/journal.pone.0045488 | |||||||||
| 権利 | ||||||||||
| 権利情報 | © Katsura, Satta | |||||||||
| 関連サイト | ||||||||||
| 識別子タイプ | URI | |||||||||
| 関連識別子 | http://www.plos.org/about/open-access/license/ | |||||||||
| 関連名称 | Copyright | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
