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The effect of selection on the amounts of nucleotide variation within and between allelic classes
https://ir.soken.ac.jp/records/3523
https://ir.soken.ac.jp/records/35239ea21639-162a-4c3e-a6da-c8b4890ac00c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2013-04-26 | |||||
| タイトル | ||||||
| タイトル | The effect of selection on the amounts of nucleotide variation within and between allelic classes | |||||
| タイトル | ||||||
| タイトル | The effect of selection on the amounts of nucleotide variation within and between allelic classes | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
INNAN, Hideki
× INNAN, Hideki× TAJIMA , Fumio |
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| 著者別名 |
印南, 秀樹
× 印南, 秀樹 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The effect of selection on the amounts of nucleotide variation within and between allelic classes was studied when two allelic classes exist in a population. Two selection models – the genic selection model and the overdominant selection model – were used. The average numbers of pairwise nucleotide differences within two allelic classes were investigated by computer simulation and the average number of pairwise differences between two allelic classes was obtained analytically. It was indicated that selection largely affects the amounts of variation within and between allelic classes. However, the sum of the average numbers of pairwise differences within two allelic classes is nearly constant and always close to θ(θ=4Nμ), even when selection is acting, where N is the effective population size and μ is the mutation rate per sequence per generation. This result suggests that the sum of the average numbers of pairwise differences within two allelic classes can be used to estimate θ. It may be useful for a region where selection may be acting. As examples, several gene regions of Drosophila melanogaster and a region of Mus domesticus were analysed. The effect of recombination on the sum of the average numbers of pairwise differences within two allelic classes was discussed. | |||||
| 書誌情報 |
Genetical Research en : Genetical Research 巻 80, 号 1, p. 15-25, 発行日 2002-08 |
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| 出版者 | ||||||
| 出版者 | Cambridge University Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00166723 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 12448854 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | http://doi.org/10.1017/S0016672302005748 | |||||
| 関連名称 | 10.1017/S0016672302005748 | |||||
| 権利 | ||||||
| 権利情報 | © Cambridge University Press | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://journals.cambridge.org/action/stream?pageId=4088&level=2#4408 | |||||
| 関連名称 | Copyright | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
