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  1. 010 学術雑誌論文
  2. 印南, 秀樹 / INNAN, Hideki

The effect of selection on the amounts of nucleotide variation within and between allelic classes

https://ir.soken.ac.jp/records/3523
https://ir.soken.ac.jp/records/3523
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Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-04-26
タイトル
タイトル The effect of selection on the amounts of nucleotide variation within and between allelic classes
タイトル
タイトル The effect of selection on the amounts of nucleotide variation within and between allelic classes
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 INNAN, Hideki

× INNAN, Hideki

INNAN, Hideki

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TAJIMA , Fumio

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TAJIMA , Fumio

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著者別名 印南, 秀樹

× 印南, 秀樹

印南, 秀樹

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内容記述タイプ Abstract
内容記述 The effect of selection on the amounts of nucleotide variation within and between allelic classes was studied when two allelic classes exist in a population. Two selection models – the genic selection model and the overdominant selection model – were used. The average numbers of pairwise nucleotide differences within two allelic classes were investigated by computer simulation and the average number of pairwise differences between two allelic classes was obtained analytically. It was indicated that selection largely affects the amounts of variation within and between allelic classes. However, the sum of the average numbers of pairwise differences within two allelic classes is nearly constant and always close to θ(θ=4Nμ), even when selection is acting, where N is the effective population size and μ is the mutation rate per sequence per generation. This result suggests that the sum of the average numbers of pairwise differences within two allelic classes can be used to estimate θ. It may be useful for a region where selection may be acting. As examples, several gene regions of Drosophila melanogaster and a region of Mus domesticus were analysed. The effect of recombination on the sum of the average numbers of pairwise differences within two allelic classes was discussed.
書誌情報 Genetical Research
en : Genetical Research

巻 80, 号 1, p. 15-25, 発行日 2002-08
出版者
出版者 Cambridge University Press
ISSN
収録物識別子タイプ ISSN
収録物識別子 00166723
PubMed番号
関連タイプ isIdenticalTo
識別子タイプ PMID
関連識別子 12448854
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 http://doi.org/10.1017/S0016672302005748
関連名称 10.1017/S0016672302005748
権利
権利情報 © Cambridge University Press
関連サイト
識別子タイプ URI
関連識別子 http://journals.cambridge.org/action/stream?pageId=4088&level=2#4408
関連名称 Copyright
フォーマット
内容記述タイプ Other
内容記述 application/pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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