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The effect of gene flow on the coalescent time in the human-chimpanzee ancestral population
https://ir.soken.ac.jp/records/3647
https://ir.soken.ac.jp/records/3647a1e7bdfa-eb79-46b1-b2b7-fdc9d9dbb2a0
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2013-06-27 | |||||||||
| タイトル | ||||||||||
| タイトル | The effect of gene flow on the coalescent time in the human-chimpanzee ancestral population | |||||||||
| タイトル | ||||||||||
| タイトル | The effect of gene flow on the coalescent time in the human-chimpanzee ancestral population | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | metadata only access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||
| 著者 |
INNAN, Hideki
× INNAN, Hideki
× WATANABE, Hidemi
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| 著者別名 |
印南, 秀樹
× 印南, 秀樹
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | The coalescent process in the human-chimpanzee ancestral population is investigated using a model, which incorporates a certain time period of gene flow during the speciation process. a is a parameter to represent the degree and time of gene flow, and the model is identical to the null model with an instantaneous species split when a = ∞. A maximum likelihood (ML) method is developed to estimate a, and its power and reliability is investigated by coalescent simulations. The ML method is applied to nucleotide divergence data between human and chimpanzee. It is found that the null model with an instantaneous species split explains the data best, and no strong evidence for gene flow is detected. The result is discussed in the view of the mode of speciation. Another ML method is developed to estimate the male-female ratio (α) of mutation rate, in which the coalescent process in the ancestral population is taken into account. | |||||||||
| 書誌情報 |
Molecular Biology and Evolution en : Molecular Biology and Evolution 巻 23, 号 5, p. 1040-1047, 発行日 2006-05 |
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| 出版者 | ||||||||||
| 出版者 | Oxford University Press | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 07374038 | |||||||||
| PubMed番号 | ||||||||||
| 識別子タイプ | PMID | |||||||||
| 関連識別子 | 16495349 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1093/molbev/msj109 | |||||||||
| 関連名称 | 10.1093/molbev/msj109 | |||||||||
| 権利 | ||||||||||
| 権利情報 | © 2013 Society for Molecular Biology and Evolution | |||||||||
