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  1. 010 学術雑誌論文
  2. 高畑, 尚之 / TAKAHATA, Naoyuki

A mathematical study on the distribution of the number of repeated genes per chromosome

https://ir.soken.ac.jp/records/3698
https://ir.soken.ac.jp/records/3698
bdf8c2b6-9000-47c1-a8d3-fea0cda814dc
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-07-02
タイトル
タイトル A mathematical study on the distribution of the number of repeated genes per chromosome
タイトル
タイトル A mathematical study on the distribution of the number of repeated genes per chromosome
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 TAKAHATA, Naoyuki

× TAKAHATA, Naoyuki

TAKAHATA, Naoyuki

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著者別名 尚之, 高畑

× 尚之, 高畑

尚之, 高畑

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抄録
内容記述タイプ Abstract
内容記述 I develop a mathematical model which can account for a distribution of the number of repeated genes per chromosome under the joint effects of sister chromatid exchange (SCE), inter-chromosomal crossing-over (ICC), and selection. The model can be applied not only to the cases of small gene clusters but also to multigene families. Based on this model, an appropriate mathematical formula is derived and used to obtain the equilibrium distribution. Assuming stabilizing selection and two simple schemes concerning SCE and ICC, I numerically calculate the equilibrium distribution and compare the result with observations on frequencies of single and triple α-haemoglobin genes in primates. It is also shown that if SCE and ICC occur according to the same probabilistic law, the distinction between them does not make much sense in the equilibrium distribution.
書誌情報 Genetical Research
en : Genetical Research

巻 38, 号 1, p. 97-102, 発行日 1981
出版者
出版者 Cambridge University Press
ISSN
収録物識別子タイプ ISSN
収録物識別子 00166723
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1017/S0016672300020437
関連名称 10.1017/S0016672300020437
権利
権利情報 © Cambridge University Press
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