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A mathematical study on the distribution of the number of repeated genes per chromosome
https://ir.soken.ac.jp/records/3698
https://ir.soken.ac.jp/records/3698bdf8c2b6-9000-47c1-a8d3-fea0cda814dc
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-07-02 | |||||
| タイトル | ||||||
| タイトル | A mathematical study on the distribution of the number of repeated genes per chromosome | |||||
| タイトル | ||||||
| タイトル | A mathematical study on the distribution of the number of repeated genes per chromosome | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
TAKAHATA, Naoyuki
× TAKAHATA, Naoyuki |
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| 著者別名 |
尚之, 高畑
× 尚之, 高畑 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | I develop a mathematical model which can account for a distribution of the number of repeated genes per chromosome under the joint effects of sister chromatid exchange (SCE), inter-chromosomal crossing-over (ICC), and selection. The model can be applied not only to the cases of small gene clusters but also to multigene families. Based on this model, an appropriate mathematical formula is derived and used to obtain the equilibrium distribution. Assuming stabilizing selection and two simple schemes concerning SCE and ICC, I numerically calculate the equilibrium distribution and compare the result with observations on frequencies of single and triple α-haemoglobin genes in primates. It is also shown that if SCE and ICC occur according to the same probabilistic law, the distinction between them does not make much sense in the equilibrium distribution. | |||||
| 書誌情報 |
Genetical Research en : Genetical Research 巻 38, 号 1, p. 97-102, 発行日 1981 |
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| 出版者 | ||||||
| 出版者 | Cambridge University Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00166723 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1017/S0016672300020437 | |||||
| 関連名称 | 10.1017/S0016672300020437 | |||||
| 権利 | ||||||
| 権利情報 | © Cambridge University Press | |||||
