Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2013-07-03 |
タイトル |
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タイトル |
Genetics and Molecular Research |
タイトル |
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タイトル |
Genetics and Molecular Research |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
アクセス権 |
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アクセス権 |
metadata only access |
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アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
著者 |
BHOWMICK, Bejon Kumar
TAKAHATA, Naoyuki
WATANABE, Motomu
SATTA, Yoko
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著者別名 |
尚之, 高畑
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
To study rapidly evolving male specific Y (MSY) genes we retrieved and analyzed nine such genes. VCY, HSFY and RBMY were found to have functional X gametologs, but the rest did not. Using chimpanzee orthologs for XKRY, CDY, HSFY, PRY, and TSPY, the average silent substitution is estimated as 0.017 ± 0.006/site and the substitution rate is 1.42 × 10 -9/site/year. Except for VCY, all other loci possess two or more pseudogenes on the Y chromosome. Sequence differences from functional genes show that BPY2, DAZ, XKRY, and RBMY each have one pseudogene for each one that is human specific, while others were generated well before the human-chimpanzee split, by means of duplication, retro-transposition or translocation. Some functional MSY gene duplication of VCY, CDY and HSFY, as well as X-linked VCX and HSFX duplication, occurred in the lineage leading to humans; these duplicates have accumulated nucleotide substitutions that permit their identification. |
書誌情報 |
Genetics and Molecular Research
en : Genetics and Molecular Research
巻 5,
号 4,
p. 696-712,
発行日 2006
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出版者 |
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出版者 |
The Ribeirão Preto foundation for Scientific Research (FUNPEC) |
ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
16765680 |
PubMed番号 |
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識別子タイプ |
PMID |
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関連識別子 |
17183480 |
権利 |
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権利情報 |
©FUNPEC-RP |
関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
http://www.funpecrp.com.br/gmr/year2006/vol4-5/pdf/gmr0221.pdf |
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関連名称 |
FUNPEC |