| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-07-04 |
| タイトル |
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タイトル |
Evolutionary history and mechanism of the Drosophila Cecropin gene family |
| タイトル |
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タイトル |
Evolutionary history and mechanism of the Drosophila Cecropin gene family |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
metadata only access |
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アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
DATE, Atsuko
SATTA, Yoko
TAKAHATA, Naoyuki
CHIGUSA, Sadao I
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| 著者別名 |
尚之, 高畑
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Upon bacterial infection, insects secrete a set of synthesized antibacterial proteins into the hemolymph and initiate synergistic destruction of invaders. Cecropin is one such antibacterial protein which is also found in vertebrates. To study the evolutionary history and mechanism of the Cecropin gene family, we determined DNA sequences of one isogenic In(3R)C and six isofemale lines of Drosophila melanogaster as well as one line of D. simulans and of D. yakuba. The phylogenetic analysis of these sequences together with those published for D. virilis and Sarcophaga peregrina reveals frequent gene re-organization. It was also found that silent nucleotide differences within D. melanogaster are quite heterogeneous across the gene region of approximately 3 kilobases and the extent of polymorphism is unusually usually high. These data suggest that the Cecropin gene region of D. melanogaster underwent intragenic recombination as well as introgression from a closely related sibling species, D. simulans. |
| 書誌情報 |
Immunogenetics
en : Immunogenetics
巻 47,
号 6,
p. 417-429,
発行日 1998
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| 出版者 |
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出版者 |
SpringerLink |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
00937711 |
| PubMed番号 |
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識別子タイプ |
PMID |
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関連識別子 |
9553148 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
http://doi.org/10.1007/s002510050379 |
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関連名称 |
10.1007/s002510050379 |
| 権利 |
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|
権利情報 |
SpringerLink(The original publication is available at www.springerlink.com) |
