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Relaxed natural selection in human populations during the Pleistocene
https://ir.soken.ac.jp/records/3728
https://ir.soken.ac.jp/records/37280b610e9a-0166-40e9-9917-aad9a4664476
| 名前 / ファイル | ライセンス | アクション |
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2_pdf (1.2 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2013-07-04 | |||||
| タイトル | ||||||
| タイトル | Relaxed natural selection in human populations during the Pleistocene | |||||
| タイトル | ||||||
| タイトル | Relaxed natural selection in human populations during the Pleistocene | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
TAKAHATA, Naoyuki
× TAKAHATA, Naoyuki |
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| 著者別名 |
尚之, 高畑
× 尚之, 高畑 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Available genetic data reveals that the human population is more variable than the chimpanzee population at the protein level, whereas the opposite is the case at the DNA level. The lower level of silent polymorphism in the human population suggests that its long-term breeding size is smaller than the chimpanzee's. The neutral theory suggests that natural selection has been relaxed in the human population under the improved environment. The possibility that the relaxation began with the emergence of Homo sapiens is examined, because it is known that H. habilis underwent for the first time dramatic changes in brain size, way of life, and culture, and that the childhood of H. erectus was already twice as long as that of chimpanzee. The relaxation hypothesis predicts that, relative to chimpanzee, some 20% of deleterious mutations became harmless under the changed environment throughout the Pleistocene. More extensive study of genetic variation in non-human primate's is necessary not only to confirm the hypothesis, but also to better understand the human genome itself. | |||||
| 書誌情報 |
Japanese Journal of Genetics en : Japanese Journal of Genetics 巻 68, 号 6, p. 539-547, 発行日 1993 |
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| 出版者 | ||||||
| 出版者 | The Genetics Society of Japan | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0021504X | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 8031575 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1266/jjg.68.539 | |||||
| 関連名称 | 10.1266/jjg.68.539 | |||||
| 権利 | ||||||
| 権利情報 | © 1993 by The Genetics Society of Japan | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/article/jjg/68/6/68_6_539/_article | |||||
| 関連名称 | J-STAGE | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/pub/html/AY04S110_ja.html | |||||
| 関連名称 | Copyright | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
