| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-07-04 |
| タイトル |
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|
タイトル |
Trans-specific Mhc polymorphism and the origin of species in primates |
| タイトル |
|
|
タイトル |
Trans-specific Mhc polymorphism and the origin of species in primates |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
KLEIN, Jan
SATTA, Yoko
TAKAHATA, Naoyuki
O'HUIGIN, Colm
|
| 著者別名 |
尚之, 高畑
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| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The major histocompatibility complex (Mhc) is a cluster of loci controlling the specific immune response in vertebrates. Mhc alleles often differ by a large number of nucleotide substitutions, some of which began to accumulate before the emergence of extant species. We have applied the theory of allelic genealogy to the primate Mhc genes with the aim of estimating the size of the founding populations. The calculations indicate that the long-term effective population size of the studied species was between 10(4) and 10(5) individuals and that it most likely never dropped below 10(3) individuals. |
| 書誌情報 |
Journal of Medical Primatology
en : Journal of Medical Primatology
巻 22,
号 0,
p. 57-64,
発行日 1993-01
|
| 出版者 |
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|
出版者 |
Wiley-Blackwell |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
00472565 |
| PubMed番号 |
|
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|
識別子タイプ |
PMID |
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関連識別子 |
8411099 |
| 関連サイト |
|
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|
識別子タイプ |
URI |
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|
関連識別子 |
http://europepmc.org/abstract/MED/8411099 |
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|
関連名称 |
Europe PubMed Central |
