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  1. 010 学術雑誌論文
  2. 颯田, 葉子 / SATTA, Yoko
  1. 010 学術雑誌論文
  2. 高畑, 尚之 / TAKAHATA, Naoyuki

Divergence Time and Population Size in the Lineage Leading to Modern Humans

https://ir.soken.ac.jp/records/3779
https://ir.soken.ac.jp/records/3779
dc2b9f4b-ad86-4d5f-b99f-a01c123b5640
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-07-09
タイトル
タイトル Divergence Time and Population Size in the Lineage Leading to Modern Humans
タイトル
タイトル Divergence Time and Population Size in the Lineage Leading to Modern Humans
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 TAKAHATA, Naoyuki

× TAKAHATA, Naoyuki

TAKAHATA, Naoyuki

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SATTA, Yoko

× SATTA, Yoko

SATTA, Yoko

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KLEIN, Jan

× KLEIN, Jan

KLEIN, Jan

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著者別名 尚之, 高畑

× 尚之, 高畑

尚之, 高畑

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抄録
内容記述タイプ Abstract
内容記述 We have developed maximum likelihood (ML) methods for comparisons of nucleotide sequences from unlinked genomic regions. In the case of a single species, the ML method primarily estimates the effective population size (Ne) under both constant size and abrupt expansion conditions. In the case of two or three species, the ML method simultaneously estimates the species divergence time and the effective size of ancestral populations. This allows us to trace the evolutionary history of the human population over the past several million years (my). Available sequences at human autosomal loci indicate Ne = 10,000 in the Late Pleistocene, a figure concordant with the results obtained from mitochondrial DNA sequence and allele-frequency data analysis, and there is no indication of population expansion. The ML analysis of two species shows that humans diverged from chimpanzees 4.6 my ago and that the human and chimpanzee clade diverged from the gorilla 7.2 my ago. Furthermore, the effective population size of humans more than 4.6 my ago is nearly 10 times larger than Ne of modern humans. The effective population size in the human lineage does not seem to have remained constant over the past several million pears. The ML model for three species predicts slightly different, but consistent results to those obtained by the two-species analysis.
書誌情報 Theoretical Population Biology
en : Theoretical Population Biology

巻 48, 号 2, p. 198-221, 発行日 1995-10
出版者
出版者 Elsevier
ISSN
収録物識別子タイプ ISSN
収録物識別子 00405809
PubMed番号
識別子タイプ PMID
関連識別子 7482371
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1006/tpbi.1995.1026
関連名称 10.1006/tpbi.1995.1026
権利
権利情報 © 1995 Academic Press.
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