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Divergence Time and Population Size in the Lineage Leading to Modern Humans
https://ir.soken.ac.jp/records/3779
https://ir.soken.ac.jp/records/3779dc2b9f4b-ad86-4d5f-b99f-a01c123b5640
Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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公開日 | 2013-07-09 | |||||||||||
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タイトル | Divergence Time and Population Size in the Lineage Leading to Modern Humans | |||||||||||
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タイトル | Divergence Time and Population Size in the Lineage Leading to Modern Humans | |||||||||||
言語 | en | |||||||||||
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言語 | eng | |||||||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
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アクセス権 | metadata only access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||||
著者 |
TAKAHATA, Naoyuki
× TAKAHATA, Naoyuki
× SATTA, Yoko
× KLEIN, Jan
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著者別名 |
尚之, 高畑
× 尚之, 高畑
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内容記述タイプ | Abstract | |||||||||||
内容記述 | We have developed maximum likelihood (ML) methods for comparisons of nucleotide sequences from unlinked genomic regions. In the case of a single species, the ML method primarily estimates the effective population size (Ne) under both constant size and abrupt expansion conditions. In the case of two or three species, the ML method simultaneously estimates the species divergence time and the effective size of ancestral populations. This allows us to trace the evolutionary history of the human population over the past several million years (my). Available sequences at human autosomal loci indicate Ne = 10,000 in the Late Pleistocene, a figure concordant with the results obtained from mitochondrial DNA sequence and allele-frequency data analysis, and there is no indication of population expansion. The ML analysis of two species shows that humans diverged from chimpanzees 4.6 my ago and that the human and chimpanzee clade diverged from the gorilla 7.2 my ago. Furthermore, the effective population size of humans more than 4.6 my ago is nearly 10 times larger than Ne of modern humans. The effective population size in the human lineage does not seem to have remained constant over the past several million pears. The ML model for three species predicts slightly different, but consistent results to those obtained by the two-species analysis. | |||||||||||
書誌情報 |
Theoretical Population Biology en : Theoretical Population Biology 巻 48, 号 2, p. 198-221, 発行日 1995-10 |
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出版者 | Elsevier | |||||||||||
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収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 00405809 | |||||||||||
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識別子タイプ | PMID | |||||||||||
関連識別子 | 7482371 | |||||||||||
DOI | ||||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.1006/tpbi.1995.1026 | |||||||||||
関連名称 | 10.1006/tpbi.1995.1026 | |||||||||||
権利 | ||||||||||||
権利情報 | © 1995 Academic Press. |