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  1. 010 学術雑誌論文
  2. 高畑, 尚之 / TAKAHATA, Naoyuki

Genealogy of neutral genes in two partially isolated populations

https://ir.soken.ac.jp/records/3781
https://ir.soken.ac.jp/records/3781
b809acfc-8b92-4d0b-b5c3-22aba4699e9d
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-07-09
タイトル
タイトル Genealogy of neutral genes in two partially isolated populations
タイトル
タイトル Genealogy of neutral genes in two partially isolated populations
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 TAKAHATA, Naoyuki

× TAKAHATA, Naoyuki

TAKAHATA, Naoyuki

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SLATKIN, Montgomery

× SLATKIN, Montgomery

SLATKIN, Montgomery

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著者別名 尚之, 高畑

× 尚之, 高畑

尚之, 高畑

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抄録
内容記述タイプ Abstract
内容記述 Gene genealogy in two partially isolated populations which diverged at a given time t in the past and have since been exchanging individuals at a constant rate m is studied based upon an analytic method for large t and a simulation method for any t. Particular attention is paid to the conditions under which neutral genes sampled from populations are mono-, para-, and polyphyletic in terms of coalescence (divergence) times of genes. It is shown that the probability of monophyly is high if M = 2Nm < 0.5 and T = t (2N) > 1, where N is the size of ancestral and descendant haploid populations, in which case most gene genealogies are likely to be concordant with the population relatedness. This probability decreases as the sample size of genes increases. On the other hand, the case where the probability of monophyly is low will be either that of M > 1 and any T or that of M < 1 and T < 1, but the clear distinction between these conditions appears very difficult to make. These results are also examined if the gene genealogy is reconstructed from nucleotide differences. It is then shown that the results based upon coalescence times remain valid if the number of nucleotide differences between any pair of genes is not much smaller than 10. To observe such large nucleotide differences in small populations and therefore infer a reliable gene genealogy, we must examine a fairly long stretch of DNA sequences.
書誌情報 Theoretical Population Biology
en : Theoretical Population Biology

巻 38, 号 3, p. 331-350, 発行日 1990-12
出版者
出版者 Elsevier
ISSN
収録物識別子タイプ ISSN
収録物識別子 00405809
PubMed番号
識別子タイプ PMID
関連識別子 2293402
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/0040-5809(90)90018-Q
関連名称 10.1016/0040-5809(90)90018-Q
権利
権利情報 © 1990 Published by Elsevier Inc.
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