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  1. 010 学術雑誌論文
  2. 高畑, 尚之 / TAKAHATA, Naoyuki

The average frequency of private alleles in a partially isolated population

https://ir.soken.ac.jp/records/3783
https://ir.soken.ac.jp/records/3783
25a65265-9f1e-498d-a1c0-0e3df4edb27b
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-07-09
タイトル
タイトル The average frequency of private alleles in a partially isolated population
タイトル
タイトル The average frequency of private alleles in a partially isolated population
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 SLATKIN, Montgomery

× SLATKIN, Montgomery

SLATKIN, Montgomery

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TAKAHATA, Naoyuki

× TAKAHATA, Naoyuki

TAKAHATA, Naoyuki

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著者別名 尚之, 高畑

× 尚之, 高畑

尚之, 高畑

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抄録
内容記述タイプ Abstract
内容記述 An analytic model is developed to explore the relationship between gene flow, selection, and genetic drift. We assume that a single copy of a mutant allele appears in a finite, partially isolated population and allow for the effects of immigration, genic selection, and mutation on the frequency of the mutant. Our concern is with the distribution of the mutant's frequency before it either is lost from the population or emigrates. Before either of these events, the allele will be a "private allele" and would be found in only one of several populations in a larger collection. Slatkin [(1985) Evolution 39, 53-65] found several simple properties of private alleles in his simulations. We use the method developed by Karlin and Tavaré [(1980) Genet. Res. 37, 33-46; (1981a), Theor. Pop. Biol. 19, 187-214; (1981b) Theor. Pop. Biol. 19, 215-229] for a model similar to ours to obtain a diffusion equation with a "killing term" and obtain the mean and variance of the mutant's frequency and its expected frequency in samples of a specified size. There is only fair agreement between the analytic results from this model and those from Slatkin's (loc. cit.) simulations. The rescaling method used to obtain the results indicates that if emigration is relatively frequent, the distribution of rare alleles is governed largely by the balance between genetic drift and emigration, with selection, mutation, and immigration playing a lesser role.
書誌情報 Theoretical Population Biology
en : Theoretical Population Biology

巻 28, 号 3, p. 314-331, 発行日 1985-12
出版者
出版者 Elsevier
ISSN
収録物識別子タイプ ISSN
収録物識別子 00405809
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/0040-5809(85)90032-2
関連名称 10.1016/0040-5809(85)90032-2
権利
権利情報 © 1985 Published by Elsevier Inc.
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