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Linkage disequilibrium of extranuclear genes under neutral mutations and random genetic drift
https://ir.soken.ac.jp/records/3784
https://ir.soken.ac.jp/records/3784d5fe0062-61b8-44f7-ae8d-afcbd818f9f1
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-07-09 | |||||
タイトル | ||||||
タイトル | Linkage disequilibrium of extranuclear genes under neutral mutations and random genetic drift | |||||
タイトル | ||||||
タイトル | Linkage disequilibrium of extranuclear genes under neutral mutations and random genetic drift | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
TAKAHATA, Naoyuki
× TAKAHATA, Naoyuki |
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著者別名 |
尚之, 高畑
× 尚之, 高畑 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | To evaluate the genetic constitution of extranuclear or non-Mendelian genes, several formulas for the variance of linkage disequilibrium (nonrandom association of linked genes) were derived under the neutral mutation hypothesis. Two kinds of the variances are mainly considered. One is the variance for the entire population and the other is the variance within a single germ cell. At equilibrium, both variances differ from that of a Mendelian population with the same parameters. In particular, when the cytoplasmic contribution from a male gamete β is small, as is found in most organisms, the effect of recombination between extranuclear genes is weak because of low within-cell heterogeneity. Then, the total variance for the entire population is large. Other important quantitites determining the variances are the number of extranuclear genomes per cell, n, and the number of cell divisions in a germ cell line per generation, λ. Unless β = 0, even a small contribution from a male gamete becomes significant depending on n and λ. | |||||
書誌情報 |
Theoretical Population Biology en : Theoretical Population Biology 巻 24, 号 1, p. 1-21, 発行日 1983-08 |
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出版者 | ||||||
出版者 | Elsevier | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00405809 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/0040-5809(83)90043-6 | |||||
関連名称 | 10.1016/0040-5809(83)90043-6 | |||||
権利 | ||||||
権利情報 | © 1983 Published by Elsevier Inc. |