| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-09-19 |
| タイトル |
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タイトル |
Chicken CD1 genes are located in the MHC: CD1 and endothelial protein C receptor genes constitute a distinct subfamily of class-I-like genes that predates the emergence of mammals |
| タイトル |
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タイトル |
Chicken CD1 genes are located in the MHC: CD1 and endothelial protein C receptor genes constitute a distinct subfamily of class-I-like genes that predates the emergence of mammals |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
MARUOKA, Takako
TANABE, Hideyuki
CHIBA, Marin
KASAHARA, Masanori
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Mammals have several major histocompatibility complex (MHC) class-I-like genes. Although some of them are assumed to have originated before the emergence of mammals, the origin of class-I-like genes is poorly understood. We analyzed here the recently released chicken draft genome sequence and identified two families of class-I-like genes: CD1 and PROCR (the gene for the endothelial protein C receptor). Chickens have two CD1 genes, designated CD1.1 and CD1.2, located in tandem ∼840 bp apart from each other. Chicken CD1.1 and CD1.2 are neither group 1- nor group 2-like, indicating that the two groups of CD1 emerged in a mammalian lineage. Although the database provides no information as to their chromosomal localization, we found that chicken CD1 genes are located adjacent to the previously characterized MHC B system contig on chromosome 16. We confirmed the linkage of CD1 to the B system by dual-color fluorescence in situ hybridization. Chickens have a single copy of PROCR. Among known class-I-like genes, PROCR is most closely related to CD1, indicating that CD1 and PROCR constitute a distinct subfamily of class-I-like genes that predates the emergence of mammals. |
| 書誌情報 |
Immunogenetics
en : Immunogenetics
巻 57,
号 8,
p. 590-600,
発行日 2005-09
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| 出版者 |
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出版者 |
SpringerLink |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0093-7711 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1007/s00251-005-0016-y |
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関連名称 |
10.1007/s00251-005-0016-y |
| 権利 |
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権利情報 |
SpringerLink(The original publication is available at www.springerlink.com) |
| 関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
http://link.springer.com/termsandconditions |
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関連名称 |
Copyright |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
| 著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
art%253A10.1007%252Fs00251-005-0016-y (236.6 kB)
