| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-10-23 |
| タイトル |
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|
タイトル |
Evolution of Genomic Structures on Mammalian Sex Chromosomes |
| タイトル |
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タイトル |
Evolution of Genomic Structures on Mammalian Sex Chromosomes |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
KATSURA, Yukako
IWASE, Mineyo
SATTA, Yoko
|
| 著者別名 |
颯田, 葉子
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| 抄録 |
|
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内容記述タイプ |
Abstract |
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内容記述 |
Throughout mammalian evolution, recombination between the two sex chromosomes was suppressed in a stepwise manner. It is thought that the suppression of recombination led to an accumulation of deleterious mutations and frequent genomic rearrangements on the Y chromosome. In this article, we review three evolutionary aspects related to genomic rearrangements and structures, such as inverted repeats (IRs) and palindromes (PDs), on the mammalian sex chromosomes. First, we describe the stepwise manner in which recombination between the X and Y chromosomes was suppressed in placental mammals and discuss a genomic rearrangement that might have led to the formation of present pseudoautosomal boundaries (PAB). Second, we describe ectopic gene conversion between the X and Y chromosomes, and propose possible molecular causes. Third, we focus on the evolutionary mode and timing of PD formation on the X and Y chromosomes. The sequence of the chimpanzee Y chromosome was recently published by two groups. Both groups suggest that rapid evolution of genomic structure occurred on the Y chromosome. Our re-analysis of the sequences confirmed the species-specific mode of human and chimpanzee Y chromosomal evolution. Finally, we present a general outlook regarding the rapid evolution of mammalian sex chromosomes. |
| 書誌情報 |
Current Genomics
en : Current Genomics
巻 13,
号 2,
p. 115-123,
発行日 2012-04
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| 出版者 |
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出版者 |
Bentham Science Publishers |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1389-2029 |
| PubMed番号 |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
PMID |
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関連識別子 |
3308322 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
http://doi.org/10.2174/138920212799860625 |
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関連名称 |
10.2174/138920212799860625 |
| 権利 |
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|
権利情報 |
© KATSURA et al. |
| 関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308322/ |
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関連名称 |
PMC |
| 関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
http://www.benthamscience.com/permission.php |
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関連名称 |
Copyright |
| フォーマット |
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内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 著者版フラグ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
CG-13-115 (1.4 MB)
