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The distribution of the ancestral haplotype in finite stepping-stone models with population expansion
https://ir.soken.ac.jp/records/4037
https://ir.soken.ac.jp/records/4037c594921a-2322-4583-847b-eba993d111ef
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-10-25 | |||||
| タイトル | ||||||
| タイトル | The distribution of the ancestral haplotype in finite stepping-stone models with population expansion | |||||
| タイトル | ||||||
| タイトル | The distribution of the ancestral haplotype in finite stepping-stone models with population expansion | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
SATTA, Yoko
× SATTA, Yoko× TAKAHATA, Naoyuki |
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| 著者別名 |
尚之, 高畑
× 尚之, 高畑 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Recent extensive analyses of human DNA polymorphism reveal that the ancestral haplotype at various genetic loci occurs almost exclusively in African samples. We develop a coalescence-based simulation method in stepping-stone models with population expansion and examine the probability (PA) that the ancestral haplotype is found in African samples and the probability (QA) that the most recent common ancestor of sampled genes occurs in Africa. These probabilities and other summary statistics are used to infer the human demographic history. It is shown that the high observed PA value cannot be explained simply by sampling bias. Rather, it suggests that the African population has been more strongly subdivided and isolated from each other than the non-African population and that there must have been some African populations which were not directly involved in the Out-of-Africa expansion in the late Pleistocene. | |||||
| 書誌情報 |
Molecular Ecology en : Molecular Ecology 巻 13, 号 4, p. 877-886, 発行日 2004-04 |
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| 出版者 | ||||||
| 出版者 | Wiley-Blackwell | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0962-1083 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1046/j.1365-294X.2003.02069.x | |||||
| 関連名称 | 10.1046/j.1365-294X.2003.02069.x | |||||
| 権利 | ||||||
| 権利情報 | © 1999-2013 John Wiley & Sons, Inc. | |||||
