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Acetylated alpha-tubulin in the connecting cilium of developing rat photoreceptors
https://ir.soken.ac.jp/records/4176
https://ir.soken.ac.jp/records/4176713eb706-19cd-4ecb-8fa5-515ef95be012
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
2145.full (875.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2014-01-23 | |||||
| タイトル | ||||||
| タイトル | Acetylated alpha-tubulin in the connecting cilium of developing rat photoreceptors | |||||
| タイトル | ||||||
| タイトル | Acetylated alpha-tubulin in the connecting cilium of developing rat photoreceptors | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
ARIKAWA, Kentaro
× ARIKAWA, Kentaro× WILLIAMS, David S |
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| 著者別名 |
蟻川, 謙太郎
× 蟻川, 謙太郎 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | PURPOSE: To examine the distribution of acetylated alpha-tubulin in the connecting cilium of rat rod photoreceptors during different stages of photoreceptor development. METHODS: An antibody found to be specific for the acetylated form of alpha-tubulin was used in immunoelectron microscopy of retinas from animals of different ages. RESULTS: All the microtubules of the connecting cilium, including those of the basal bodies, were found to contain acetylated alpha-tubulin at the earliest stage of outer segment development, before the cilium has begun to grow out from the cell, and at all subsequent stages. CONCLUSIONS: These results indicate that the alpha-tubulin of the connecting cilium is acetylated either before, or at least very soon after, its assembly into microtubules. Given that acetylation of alpha-tubulin is correlated with stable microtubules, the results suggest that stable microtubules might be important in creating the foundation for the formation of the outer segment, as well as in helping maintain the polarity of the mature photoreceptor. | |||||
| 書誌情報 |
Investigative Ophthalmology & Visual Science en : Investigative Ophthalmology & Visual Science 巻 34, 号 6, p. 2145-2149, 発行日 1993-05 |
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| 出版者 | ||||||
| 出版者 | Association for Research in Vision and Ophthalmology | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0146-0404 | |||||
| 権利 | ||||||
| 権利情報 | © Association for Research in Vision and Ophthalmology | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.iovs.org/site/misc/IOVScopyrightform.pdf | |||||
| 関連名称 | Copyright | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://iovs.arvojournals.org/article.aspx?articleid=2179576 | |||||
| 関連名称 | Association for Research in Vision and Ophthalmology | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
