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Photodynamic action in Stentor coeruleus sensitized by endogenous pigment stentorin.
https://ir.soken.ac.jp/records/4219
https://ir.soken.ac.jp/records/4219ac67ff44-c4be-4bb9-ac46-339f4853a2f5
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-02-05 | |||||
| タイトル | ||||||
| タイトル | Photodynamic action in Stentor coeruleus sensitized by endogenous pigment stentorin. | |||||
| タイトル | ||||||
| タイトル | Photodynamic action in Stentor coeruleus sensitized by endogenous pigment stentorin. | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
YANG, Ki-Chun
× YANG, Ki-Chun× WATANABE, Masakatsu× et, al. |
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| 著者別名 |
渡辺, 正勝
× 渡辺, 正勝 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Stentorin acts as the photoreceptor for the step-up photophobic and negative phototactic responses in Stentor coeruleus. The chromophore of stentorin appears to be hypericin which is linked to apoprotein. In addition to the photomovement responses of the organism, S. coeruleus was found to be photodynamically sensitive to light absorbed by the hypericin chromophore, as the apparent action spectrum for the photodynamic killing matches the absorption spectrum of stentorin. The protective effect of β-carotene and crocetin on the photodynamic killing of S. coeruleus suggests that singlet oxygen generated by the stentorin-sensitization plays an important role, according to the so-called Type II mechanism of photosensitization. The generation of singlet oxygen via hypericin triplet was confirmed by in vitro photooxidation of tryptophan as a substrate. The photodynamic killing was more effective in deuterium oxide than in H2O in both the photosensitization by stentorin (endogenous) and added hypericin (exogenous). These results are consistent with the involvement of singlet oxygen in the photodynamic killing of S. coeruleus. | |||||
| 書誌情報 |
Photochemistry and Photobiology en : Photochemistry and Photobiology 巻 43, 号 3, p. 305-310, 発行日 1986-03 |
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| 出版者 | ||||||
| 出版者 | Wiley | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0031-8655 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1111/j.1751-1097.1986.tb05609.x | |||||
| 関連名称 | 10.1111/j.1751-1097.1986.tb05609.x | |||||
| 権利 | ||||||
| 権利情報 | © 1999-2014 John Wiley & Sons, Inc. | |||||
