{"_buckets": {"deposit": "009b9a42-3f09-480a-8285-d100fc635172"}, "_deposit": {"created_by": 21, "id": "4305", "owners": [21], "pid": {"revision_id": 0, "type": "depid", "value": "4305"}, "status": "published"}, "_oai": {"id": "oai:ir.soken.ac.jp:00004305", "sets": ["323"]}, "author_link": ["2513", "2361", "2364", "2495"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "93", "bibliographicPageStart": "77", "bibliographicVolumeNumber": "28", "bibliographic_titles": [{"bibliographic_title": "Journal of Biological Physics"}, {"bibliographic_title": "Journal of Biological Physics", "bibliographic_titleLang": "en"}]}]}, "item_10001_creator_3": {"attribute_name": "著者別名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "桑島, 邦博"}], "nameIdentifiers": [{"nameIdentifier": "2364", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000070091444", "nameIdentifierScheme": "NRID", "nameIdentifierURI": " "}, {"nameIdentifier": "70091444", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=70091444"}]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We studied the effect of GroEL on the kinetic refolding ofα-lactalbumin by stopped-flow fluorescence techniques. We usedwild-type GroEL and its ATPase-defficient mutant D398A, and studied thebinding constants between GroEL and the molten globule foldingintermediate at various concentrations of ADP and ATP. The results arecompared with titration of GroEL with the nucleotides, ADP, ATP-analogs(ATP-γS and AMP-PNP) and ATP, which have shown that bothADP and the ATP analogs are bound to GroEL in a non-cooperativemanner but that ATP shows a cooperative effect. Similarly, the bindingconstant between GroEL and the folding intermediate decreased in acooperative manner with an increase in ATP concentration although itshowed non-cooperative decrease with respect to ADP concentration. Itis shown that the allosteric control of GroEL by the nucleotides isresponsible for the above behavior of GroEL and that the observeddifference between the ATP- and ADP-induced transitions of GroEL isbrought about by a small difference in an allosteric parameter (the ratio ofthe nucleotide affinities of GroEL in the high-affinity and the low-affinitystates), i.e., 4.1 for ATP and 2.6 for ADP.", "subitem_description_type": "Abstract"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "SpringerLink"}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1023/A:1019993102869"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1023/A:1019993102869", "subitem_relation_type_select": "DOI"}}]}, "item_10001_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "SpringerLink(The original publication is available at www.springerlink.com) "}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0092-0606", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "KUWAJIMA, Kunihiro "}], "nameIdentifiers": [{"nameIdentifier": "2361", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TADASHI, Makio"}], "nameIdentifiers": [{"nameIdentifier": "2495", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "INOBE, Tomonao "}], "nameIdentifiers": [{"nameIdentifier": "2513", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Chaperonin-Affected Folding of Globular Proteins", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Chaperonin-Affected Folding of Globular Proteins"}, {"subitem_title": "Chaperonin-Affected Folding of Globular Proteins", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "21", "path": ["323"], "permalink_uri": "https://ir.soken.ac.jp/records/4305", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-03-17"}, "publish_date": "2014-03-17", "publish_status": "0", "recid": "4305", "relation": {}, "relation_version_is_last": true, "title": ["Chaperonin-Affected Folding of Globular Proteins"], "weko_shared_id": 21}