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Surprisingly high correlation between early and late stages in non-two-state protein folding
https://ir.soken.ac.jp/records/4328
https://ir.soken.ac.jp/records/432853a6a626-3d35-4554-b30a-471664f5f6e6
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2014-03-24 | |||||||||
| タイトル | ||||||||||
| タイトル | Surprisingly high correlation between early and late stages in non-two-state protein folding | |||||||||
| タイトル | ||||||||||
| タイトル | Surprisingly high correlation between early and late stages in non-two-state protein folding | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | metadata only access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||
| 著者 |
KAMAGATA, Kiyoto
× KAMAGATA, Kiyoto
× KUWAJIMA, Kunihiro
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| 著者別名 |
桑島, 邦博
× 桑島, 邦博
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | We collected quantitative kinetic data on early and late stages of folding in non-two-state proteins from the literature, and studied the relationship between the kinetics of the two stages. There was a surprisingly high correlation between the rate constants of these stages. The correlation coefficient of the logarithmic rate constants was as high as 0.97, which could not be caused by chance. We also studied relationships of the logarithmic rate constants of the two stages with native three-dimensional structures represented by the residue–residue contact map. There were again surprisingly high correlations between the logarithmic rate constants and the number of non-local contact clusters obtained from the contact maps. Because the number of non-local contact clusters represents overall arrangement of substructures in a native protein, the results strongly suggested the importance of the arrangement of the substructures for the kinetics of both early and late stages of protein folding. | |||||||||
| 書誌情報 |
Journal of Molecular Biology en : Journal of Molecular Biology 巻 357, 号 5, p. 1647-1654, 発行日 2006-04-14 |
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| 出版者 | ||||||||||
| 出版者 | Elsevier | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0022-2836 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1016/j.jmb.2006.01.072 | |||||||||
| 関連名称 | 10.1016/j.jmb.2006.01.072 | |||||||||
| 権利 | ||||||||||
| 権利情報 | © 2006 Elsevier Ltd. | |||||||||
