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The Genealogy of Sequences Containing Multiple Sites Subject to Strong Selection in a Subdivided Population
https://ir.soken.ac.jp/records/4432
https://ir.soken.ac.jp/records/443271ed05a9-94a5-49be-832c-6763239e81c5
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-04-18 | |||||
| タイトル | ||||||
| タイトル | The Genealogy of Sequences Containing Multiple Sites Subject to Strong Selection in a Subdivided Population | |||||
| タイトル | ||||||
| タイトル | The Genealogy of Sequences Containing Multiple Sites Subject to Strong Selection in a Subdivided Population | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
NORDBORG, Magnus
× NORDBORG, Magnus× INNAN, Hideki |
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| 著者別名 |
印南, 秀樹
× 印南, 秀樹 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A stochastic model for the genealogy of a sample of recombining sequences containing one or more sites subject to selection in a subdivided population is described. Selection is incorporated by dividing the population into allelic classes and then conditioning on the past sizes of these classes. The past allele frequencies at the selected sites are thus treated as parameters rather than as random variables. The purpose of the model is not to investigate the dynamics of selection, but to investigate effects of linkage to the selected sites on the genealogy of the surrounding chromosomal region. This approach is useful for modeling strong selection, when it is natural to parameterize the past allele frequencies at the selected sites. Several models of strong balancing selection are used as examples, and the effects on the pattern of neutral polymorphism in the chromosomal region are discussed. We focus in particular on the statistical power to detect balancing selection when it is present. | |||||
| 書誌情報 |
Genetics en : Genetics 巻 163, 号 3, p. 1201-1213, 発行日 2003-03-01 |
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| 出版者 | ||||||
| 出版者 | The Genetics Society of America | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0016-6731 | |||||
| 権利 | ||||||
| 権利情報 | © 2003 by The Genetics Society of America | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.genetics.org/content/genetics/163/3/1201.full.pdf | |||||
| 関連名称 | The Genetics Society of America | |||||
