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Pattern of polymorphism after strong artificial selection in a domestication event
https://ir.soken.ac.jp/records/4440
https://ir.soken.ac.jp/records/4440c91f6827-c9f0-4bb2-a162-6b0e69ff0491
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-04-21 | |||||
タイトル | ||||||
タイトル | Pattern of polymorphism after strong artificial selection in a domestication event | |||||
タイトル | ||||||
タイトル | Pattern of polymorphism after strong artificial selection in a domestication event | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
INNAN, Hideki
× INNAN, Hideki× KIM, Yuseob |
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著者別名 |
印南, 秀樹
× 印南, 秀樹 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The process of strong artificial selection during a domestication event is modeled, and its effect on the pattern of DNA polymorphism is investigated. The model also considers population bottleneck during domestication. Artificial selection during domestication is different from a regular selective sweep because artificial selection acts on alleles that may have been neutral variants before domestication. Therefore, the fixation of such a beneficial allele does not always wipe out DNA variation in the surrounding region. The amount by which variation is reduced largely depends on the initial frequency of the beneficial allele, p. As a consequence, p has a strong effect on the likelihood of detecting the signature of selection during domestication from patterns of polymorphism. These theoretical results are discussed in light of data collected from maize. Although the main focus of this article is on domestication, this model can also be generalized to describe selective sweeps from standing genetic variation. | |||||
書誌情報 |
Proceedings of the National Academy of Sciences of the United States of America en : Proceedings of the National Academy of Sciences of the United States of America 巻 101, 号 29, p. 10667-10672, 発行日 2004-06-15 |
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出版者 | ||||||
出版者 | National Academy of Sciences | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 10916490 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1073/pnas.0401720101 | |||||
関連名称 | 10.1073/pnas.0401720101 | |||||
権利 | ||||||
権利情報 | © 2004, The National Academy of Sciences |