| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2014-04-21 |
| タイトル |
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タイトル |
The Probability and Chromosomal Extent of trans-specific Polymorphism |
| タイトル |
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タイトル |
The Probability and Chromosomal Extent of trans-specific Polymorphism |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
metadata only access |
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アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
WIUF, Carsten
ZHAO, Keyan
INNAN, Hideki
NORDBORG, Magnus
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| 著者別名 |
印南, 秀樹
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Balancing selection may result in trans-specific polymorphism: the maintenance of allelic classes that transcend species boundaries by virtue of being more ancient than the species themselves. At the selected site, gene genealogies are expected not to reflect the species tree. Because of linkage, the same will be true for part of the surrounding chromosomal region. Here we obtain various approximations for the distribution of the length of this region and discuss the practical implications of our results. Our main finding is that the trans-specific region surrounding a single-locus balanced polymorphism is expected to be quite short, probably too short to be readily detectable. Thus lack of obvious trans-specific polymorphism should not be taken as evidence against balancing selection. When trans-specific polymorphism is obvious, on the other hand, it may be reasonable to argue that selection must be acting on multiple sites or that recombination is suppressed in the surrounding region. |
| 書誌情報 |
Genetics
en : Genetics
巻 168,
号 4,
p. 2363-2372,
発行日 2004-12-01
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| 出版者 |
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出版者 |
The Genetics Society of America |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0016-6731 |
| 権利 |
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権利情報 |
© The Genetics Society of America |
| 関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
http://www.genetics.org/content/genetics/168/4/2363.full.pdf |
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関連名称 |
The Genetics Society of America |
