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  1. 010 学術雑誌論文
  2. 印南, 秀樹 / INNAN, Hideki

Statistical Tests of the Coalescent Model Based on the Haplotype Frequency Distribution and the Number of Segregating Sites

https://ir.soken.ac.jp/records/4451
https://ir.soken.ac.jp/records/4451
1ad50d97-3d98-4ceb-91b5-cd51f1b32b20
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-04-22
タイトル
タイトル Statistical Tests of the Coalescent Model Based on the Haplotype Frequency Distribution and the Number of Segregating Sites
タイトル
言語 en
タイトル Statistical Tests of the Coalescent Model Based on the Haplotype Frequency Distribution and the Number of Segregating Sites
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 INNAN, Hideki

× INNAN, Hideki

WEKO 342

INNAN, Hideki

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et, al.

× et, al.

WEKO 3119

et, al.

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著者別名 印南, 秀樹

× 印南, 秀樹

WEKO 341
NRID 1000090444140
e-Rad 90444140

印南, 秀樹

Search repository
抄録
内容記述タイプ Abstract
内容記述 Several tests of neutral evolution employ the observed number of segregating sites and properties of the haplotype frequency distribution as summary statistics and use simulations to obtain rejection probabilities. Here we develop a “haplotype configuration test” of neutrality (HCT) based on the full haplotype frequency distribution. To enable exact computation of rejection probabilities for small samples, we derive a recursion under the standard coalescent model for the joint distribution of the haplotype frequencies and the number of segregating sites. For larger samples, we consider simulation-based approaches. The utility of the HCT is demonstrated in simulations of alternative models and in application to data from Drosophila melanogaster.
書誌情報 Genetics
en : Genetics

巻 169, 号 3, 発行日 2005-03-01
出版者
出版者 The Genetics Society of America
ISSN
収録物識別子タイプ ISSN
収録物識別子 0016-6731
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1534/genetics.104.031955
関連名称 10.1534/genetics.104.032219
権利
権利情報 © The Genetics Society of America
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