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Molecular Evolution of Pathogenicity-Island Genes in Pseudomonas viridiflava
https://ir.soken.ac.jp/records/4466
https://ir.soken.ac.jp/records/4466273faed3-9053-4abe-805b-5424713c7fa3
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-05-07 | |||||
| タイトル | ||||||
| タイトル | Molecular Evolution of Pathogenicity-Island Genes in Pseudomonas viridiflava | |||||
| タイトル | ||||||
| タイトル | Molecular Evolution of Pathogenicity-Island Genes in Pseudomonas viridiflava | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
ARAKI, Hitoshi
× ARAKI, Hitoshi× INNAN, Hideki× KREITMAN, Martin× BERGELSON, Joy |
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| 著者別名 |
印南, 秀樹
× 印南, 秀樹 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The bacterial pathogen Pseudomonas viridiflava possesses two pathogenicity islands (PAIs) that share many gene homologs, but are structurally and phenotypically differentiated (T-PAI and S-PAI). These PAIs are paralogous, but only one is present in each isolate. While this dual presence/absence polymorphism has been shown to be maintained by balancing selection, little is known about the molecular evolution of individual genes on the PAIs. Here we investigate genetic variation of 12 PAI gene loci (7 on T-PAI and 5 on S-PAI) in 96 worldwide isolates of P. viridiflava. These genes include avirulence genes (hopPsyA and avrE), their putative chaperones (shcA and avrF), and genes encoding the type III outer proteins (hrpA, hrpZ, and hrpW). Average nucleotide diversities in these genes (π = 0.004–0.020) were close to those in the genetic background. Large numbers of recombination events were found within PAIs and a sign of positive selection was detected in avrE. These results suggest that the PAI genes are evolving relatively freely from each other on the PAIs, rather than as a single unit under balancing selection. Evolutionarily stable PAIs may be preferable in this species because preexisting genetic variation enables P. viridiflava to respond rapidly to natural selection. | |||||
| 書誌情報 |
Genetics en : Genetics 巻 177, 号 2, p. 1031-1041, 発行日 2007-10 |
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| 出版者 | ||||||
| 出版者 | The Genetics Society of America | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0016-6731 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1534/genetics.107.077925 | |||||
| 関連名称 | 10.1534/genetics.107.077925 | |||||
| 権利 | ||||||
| 権利情報 | © 2007 by The Genetics Society of America | |||||
