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Selection to maintain paralogous amino acid differences under the pressure of gene conversion in the heat shock protein genes in yeast
https://ir.soken.ac.jp/records/4487
https://ir.soken.ac.jp/records/4487f15d4241-378b-432a-ac3f-869d7fbef742
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2014-05-09 | |||||||||
| タイトル | ||||||||||
| タイトル | Selection to maintain paralogous amino acid differences under the pressure of gene conversion in the heat shock protein genes in yeast | |||||||||
| タイトル | ||||||||||
| タイトル | Selection to maintain paralogous amino acid differences under the pressure of gene conversion in the heat shock protein genes in yeast | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | metadata only access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||
| 著者 |
TAKUNO, Shohei
× TAKUNO, Shohei
× INNAN, Hideki
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| 著者別名 |
印南, 秀樹
× 印南, 秀樹
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | A genome scan for the signatures of selection for paralogous functional amino acid differences was performed with yeast genomes. This recently developed method makes it possible to localize the target sites of selection under the pressure of gene conversion. We found that two gene pairs have strong signatures of selection. The two pairs of duplicated genes happened to be heat shock genes (Ssa1/ Ssa2 and Ssb1/Ssb2), which have similar protein structures to each other, although the amino acid sequence identity between Ssa and Ssb is not high (∼60%). Interestingly, the two gene pairs exhibit signature of selection at almost identical positions within the substrate-binding domain β. Because this domain specifies the substrate polypeptides, it is presumed that functional divergence may be advantageous in this domain. Evolutionary analysis demonstrated that the observed divergence in the two gene pairs has been maintained in many yeast species independently, suggesting long-term operation of strong selection. | |||||||||
| 書誌情報 |
Molecular Biology and Evolution en : Molecular Biology and Evolution 巻 26, 号 12, p. 2655-2659, 発行日 2009 |
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| 出版者 | ||||||||||
| 出版者 | Oxford University Press | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0737-4038 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1093/molbev/msp211 | |||||||||
| 関連名称 | 10.1093/molbev/msp211 | |||||||||
| 権利 | ||||||||||
| 権利情報 | © The Author 2009. | |||||||||
