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  1. 010 学術雑誌論文
  2. 印南, 秀樹 / INNAN, Hideki
  1. 010 学術雑誌論文
  2. 宅野, 将平 / TAKUNO, Shohei

Selection to maintain paralogous amino acid differences under the pressure of gene conversion in the heat shock protein genes in yeast

https://ir.soken.ac.jp/records/4487
https://ir.soken.ac.jp/records/4487
f15d4241-378b-432a-ac3f-869d7fbef742
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-05-09
タイトル
タイトル Selection to maintain paralogous amino acid differences under the pressure of gene conversion in the heat shock protein genes in yeast
タイトル
タイトル Selection to maintain paralogous amino acid differences under the pressure of gene conversion in the heat shock protein genes in yeast
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 TAKUNO, Shohei

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TAKUNO, Shohei

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INNAN, Hideki

× INNAN, Hideki

INNAN, Hideki

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著者別名 印南, 秀樹

× 印南, 秀樹

印南, 秀樹

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抄録
内容記述タイプ Abstract
内容記述 A genome scan for the signatures of selection for paralogous functional amino acid differences was performed with yeast genomes. This recently developed method makes it possible to localize the target sites of selection under the pressure of gene conversion. We found that two gene pairs have strong signatures of selection. The two pairs of duplicated genes happened to be heat shock genes (Ssa1/ Ssa2 and Ssb1/Ssb2), which have similar protein structures to each other, although the amino acid sequence identity between Ssa and Ssb is not high (∼60%). Interestingly, the two gene pairs exhibit signature of selection at almost identical positions within the substrate-binding domain β. Because this domain specifies the substrate polypeptides, it is presumed that functional divergence may be advantageous in this domain. Evolutionary analysis demonstrated that the observed divergence in the two gene pairs has been maintained in many yeast species independently, suggesting long-term operation of strong selection.
書誌情報 Molecular Biology and Evolution
en : Molecular Biology and Evolution

巻 26, 号 12, p. 2655-2659, 発行日 2009
出版者
出版者 Oxford University Press
ISSN
収録物識別子タイプ ISSN
収録物識別子 0737-4038
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1093/molbev/msp211
関連名称 10.1093/molbev/msp211
権利
権利情報 © The Author 2009.
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