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The power of the methods for detecting interlocus gene conversion
https://ir.soken.ac.jp/records/4494
https://ir.soken.ac.jp/records/44944628b3cb-28c0-42d5-9eb4-9e303fa32272
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2014-05-12 | |||||||||
| タイトル | ||||||||||
| タイトル | The power of the methods for detecting interlocus gene conversion | |||||||||
| タイトル | ||||||||||
| タイトル | The power of the methods for detecting interlocus gene conversion | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | metadata only access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||
| 著者 |
MANSAI, Sayaka P.
× MANSAI, Sayaka P.
× INNAN, Hideki
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| 著者別名 |
印南, 秀樹
× 印南, 秀樹
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Interlocus gene conversion can homogenize DNA sequences of duplicated regions with high homology. Such nonvertical events sometimes cause a misleading evolutionary interpretation of data when the effect of gene conversion is ignored. To avoid this problem, it is crucial to test the data for the presence of gene conversion. Here, we performed extensive simulations to compare four major methods to detect gene conversion. One might expect that the power increases with increase of the gene conversion rate. However, we found this is true for only two methods. For the other two, limited power is expected when gene conversion is too frequent. We suggest using multiple methods to minimize the chance of missing the footprint of gene conversion. | |||||||||
| 書誌情報 |
Genetics en : Genetics 巻 184, 号 2, p. 517-527, 発行日 2010-02 |
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| 出版者 | ||||||||||
| 出版者 | The Genetics Society of America | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0016-6731 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1534/genetics.109.111161 | |||||||||
| 関連名称 | 10.1534/genetics.109.111161 | |||||||||
| 権利 | ||||||||||
| 権利情報 | © 2010 by The Genetics Society of America | |||||||||
