{"_buckets": {"deposit": "c5148a65-3483-4f58-bdaa-93fcf3f0ee9e"}, "_deposit": {"created_by": 21, "id": "4510", "owners": [21], "pid": {"revision_id": 0, "type": "depid", "value": "4510"}, "status": "published"}, "_oai": {"id": "oai:ir.soken.ac.jp:00004510", "sets": ["275"]}, "author_link": ["342", "341", "2694", "2750"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "9", "bibliographicPageEnd": "2196", "bibliographicPageStart": "2187", "bibliographicVolumeNumber": "30", "bibliographic_titles": [{"bibliographic_title": "Molecular Biology and Evolution "}, {"bibliographic_title": "Molecular Biology and Evolution ", "bibliographic_titleLang": "en"}]}]}, "item_10001_creator_3": {"attribute_name": "著者別名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "印南, 秀樹"}], "nameIdentifiers": [{"nameIdentifier": "341", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000090444140", "nameIdentifierScheme": "NRID", "nameIdentifierURI": " "}, {"nameIdentifier": "90444140", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=90444140"}]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "When we sequence a diploid individual, the output actually comprises two genomes: one from the paternal parent and the other from the maternal parent. In this study, we introduce a novel heuristic algorithm for distinguishing single-nucleotide polymorphisms (SNPs) from the two parents and phasing them into haplotypes. The algorithm is unique because it simultaneously performs SNP calling and haplotype phasing. This approach can exploit the linkage information of nearby SNPs, which facilitates the efficient removal of haplotypes that originate from incorrectly mapped short reads. Using simulated data we demonstrated that our approach increased the accuracy of SNP calls. The haplotype reconstruction performance depended largely on the density of SNPs. Using current next-generation sequence technology with a relatively short read length, reasonable performance is expected when this approach is applied to species with an average of five heterozygous sites per 1 kb. The algorithm was implemented as the program “linkSNPs.” ", "subitem_description_type": "Abstract"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Oxford University Press "}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1093/molbev/mst103"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1093/molbev/mst103", "subitem_relation_type_select": "DOI"}}]}, "item_10001_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© The Author 2013."}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "07374038 ", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "SASAKI, Eriko "}], "nameIdentifiers": [{"nameIdentifier": "2750", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "SUGINO, Ryuichi P. "}], "nameIdentifiers": [{"nameIdentifier": "2694", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "INNAN, Hideki"}], "nameIdentifiers": [{"nameIdentifier": "342", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "The linkage method, a novel approach for SNP detection and haplotype reconstruction from a single diploid individual with next generation sequence data", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "The linkage method, a novel approach for SNP detection and haplotype reconstruction from a single diploid individual with next generation sequence data"}, {"subitem_title": "The linkage method, a novel approach for SNP detection and haplotype reconstruction from a single diploid individual with next generation sequence data", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "21", "path": ["117", "275"], "permalink_uri": "https://ir.soken.ac.jp/records/4510", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-05-14"}, "publish_date": "2014-05-14", "publish_status": "0", "recid": "4510", "relation": {}, "relation_version_is_last": true, "title": ["The linkage method, a novel approach for SNP detection and haplotype reconstruction from a single diploid individual with next generation sequence data"], "weko_shared_id": 21}