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The complexity of alternative splicing of hagoromo mRNAs is increased in an explosively speciated lineage in East African cichlids
https://ir.soken.ac.jp/records/4677
https://ir.soken.ac.jp/records/4677bcafbf28-1e23-4d82-bf38-e52d2c8e0018
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-06-23 | |||||
| タイトル | ||||||
| タイトル | The complexity of alternative splicing of hagoromo mRNAs is increased in an explosively speciated lineage in East African cichlids | |||||
| タイトル | ||||||
| タイトル | The complexity of alternative splicing of hagoromo mRNAs is increased in an explosively speciated lineage in East African cichlids | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
TERAI, Yohey
× TERAI, Yohey× MORIKAWA, Naoko× KAWAKAMI, Koichi× OKADA, Norihiro |
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| 著者別名 |
寺井, 洋平
× 寺井, 洋平 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The adaptive radiation of cichlid fishes in the lakes of East Africa is a prime example of speciation. The choice of cichlid mates on the basis of a variety of coloration represents a potential basis for speciation that led to adaptive radiation. Here, we characterize the cichlid homolog of the zebrafish hagoromo (hag) gene that was recently cloned and characterized from a pigmentation mutant. Although only one hag mRNA was reported in zebrafish, cichlids express nine different hag mRNAs resulting from alternative splicing. The hag mRNAs are expressed between the myotome and the epidermis where pigment cells are located, suggesting the cichlid hag gene is involved in pigmentation. The hag mRNA splicing pattern does not fluctuate among individuals from each of two species, suggesting that alternative splice site choice is fixed within species. Furthermore, cichlids in lineages that underwent explosive speciation expressed a greater variety of hag mRNAs than those in lineages that did not undergo such a degree of speciation, suggesting that species in the explosively speciated lineage acquired a complex regulatory mechanism of alternative splicing over a very short evolutionary period. Here, we provide an example in which alternative splicing may play a role in mate choice, leading to cichlid speciation through diversification of gene function by production of multiple mRNAs from a single gene. | |||||
| 書誌情報 |
Proceedings of the National Academy of Sciences of the United States of America en : Proceedings of the National Academy of Sciences of the United States of America 巻 100, 号 22, p. 12798-12803, 発行日 2003-10 |
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| 出版者 | ||||||
| 出版者 | National Academy of Sciences | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1091-6490 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1073/pnas.2132833100 | |||||
| 関連名称 | 10.1073/pnas.2132833100 | |||||
| 権利 | ||||||
| 権利情報 | © 2003, The National Academy of Sciences | |||||
