{"_buckets": {"deposit": "d1213f98-625d-4c52-ba65-4126beaec228"}, "_deposit": {"created_by": 20, "id": "5261", "owners": [20], "pid": {"revision_id": 0, "type": "depid", "value": "5261"}, "status": "published"}, "_oai": {"id": "oai:ir.soken.ac.jp:00005261", "sets": ["345"]}, "author_link": ["4535", "4539", "4541", "4540", "4538", "4536", "4537"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014-12-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "245", "bibliographicPageStart": "239", "bibliographicVolumeNumber": "552", "bibliographic_titles": [{"bibliographic_title": "Gene"}, {"bibliographic_title": "Gene", "bibliographic_titleLang": "en"}]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "When a population size is reduced, genetic drift may fix slightly deleterious mutations, and an increase in nonsynonymous substitution is expected. It has been suggested that past aridity has seriously affected and decreased the populations of cichlid fishes in Lake Victoria, while geographical studies have shown that the water levels in Lake Tanganyika and Lake Malawi have remained fairly constant. The comparably stable environments in the latter two lakes might have kept the populations of cichlid fishes large enough to remove slightly deleterious mutations. The difference in the stability of cichlid fish population sizes between Lake Victoria and the Lakes Tanganyika and Malawi is expected to have caused differences in the nonsynonymous/synonymous ratio, ω (=dN/dS), of the evolutionary rate. Here, we estimated ω and compared it between the cichlids of the three lakes for 13 mitochondrial protein-coding genes using maximum likelihood methods. We found that the lineages of the cichlids in Lake Victoria had a significantly higher ω for several mitochondrial loci. Moreover, positive selection was indicated for several codons in the mtDNA of the Lake Victoria cichlid lineage. Our results indicate that both adaptive and slightly deleterious molecular evolution has taken place in the Lake Victoria cichlids\u0027 mtDNA genes, whose nonsynonymous sites are generally conserved.", "subitem_description_type": "Abstract"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier/North-Holland Biomedical Press / Amsterdam"}]}, "item_10001_relation_13": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "25241383", "subitem_relation_type_select": "PMID"}}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.gene.2014.09.039 ＜ScienceDirect Abstract＞ "}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://dx.doi.org/10.1016/j.gene.2014.09.039", "subitem_relation_type_select": "DOI"}}]}, "item_10001_relation_17": {"attribute_name": "関連サイト", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "Gene ＜Elsevier ScienceDirect＞"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.sciencedirect.com/science/journal/03781119", "subitem_relation_type_select": "URI"}}]}, "item_10001_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2014 Elsevier B.V. All rights reserved."}]}, "item_10001_source_id_11": {"attribute_name": "書誌レコードID (NCID)", "attribute_value_mlt": [{"subitem_source_identifier": "AA11529840", "subitem_source_identifier_type": "NCID"}, {"subitem_source_identifier": "AA00654385", "subitem_source_identifier_type": "NCID"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0378-1119", "subitem_source_identifier_type": "ISSN"}]}, "item_10001_text_23": {"attribute_name": "著者注記", "attribute_value_mlt": [{"subitem_text_value": "Yohey, Terai : Department of Biosystems Science, The Graduate University for Advanced Studies (Sokendai) *(Assistant Professor)"}]}, "item_10001_text_25": {"attribute_name": "雑誌情報", "attribute_value_mlt": [{"subitem_text_value": "Vol. 1, no. 1 (1976)-"}, {"subitem_text_value": "Frequency : Biweekly"}]}, "item_10001_text_28": {"attribute_name": "論文注記", "attribute_value_mlt": [{"subitem_text_value": "Available online 18 September 2014"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "SHIRAI, Kazumasa"}], "nameIdentifiers": [{"nameIdentifier": "4535", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "INOMATA, Kazumasa"}], "nameIdentifiers": [{"nameIdentifier": "4536", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MIZOIRI, Shinji"}], "nameIdentifiers": [{"nameIdentifier": "4537", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "AIBARA, Mitsuto"}], "nameIdentifiers": [{"nameIdentifier": "4538", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TERAI, Yohey"}], "nameIdentifiers": [{"nameIdentifier": "4539", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "OKADA, Norihiro"}], "nameIdentifiers": [{"nameIdentifier": "4540", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TACHIDA, Hidenori"}], "nameIdentifiers": [{"nameIdentifier": "4541", "nameIdentifierScheme": "WEKO"}]}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Amino Acid Substitution", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Animals", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cichlids", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "DNA, Mitochondrial", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Fish Proteins", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Genetics, Population", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Lakes", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Likelihood Functions", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Mutation", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Phylogeny", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "High prevalence of non-synonymous substitutions in mtDNA of cichlid fishes from Lake Victoria.", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "High prevalence of non-synonymous substitutions in mtDNA of cichlid fishes from Lake Victoria."}, {"subitem_title": "High prevalence of non-synonymous substitutions in mtDNA of cichlid fishes from Lake Victoria.", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "20", "path": ["344", "345"], "permalink_uri": "https://ir.soken.ac.jp/records/5261", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-01-01"}, "publish_date": "2016-01-01", "publish_status": "0", "recid": "5261", "relation": {}, "relation_version_is_last": true, "title": ["High prevalence of non-synonymous substitutions in mtDNA of cichlid fishes from Lake Victoria."], "weko_shared_id": 20}