| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2016-01-01 |
| タイトル |
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|
タイトル |
High prevalence of non-synonymous substitutions in mtDNA of cichlid fishes from Lake Victoria. |
| タイトル |
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|
タイトル |
High prevalence of non-synonymous substitutions in mtDNA of cichlid fishes from Lake Victoria. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Amino Acid Substitution |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Animals |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Cichlids |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
DNA, Mitochondrial |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Fish Proteins |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Genetics, Population |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Lakes |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Likelihood Functions |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Mutation |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Phylogeny |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
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アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
SHIRAI, Kazumasa
INOMATA, Kazumasa
MIZOIRI, Shinji
AIBARA, Mitsuto
TERAI, Yohey
OKADA, Norihiro
TACHIDA, Hidenori
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| 著者注記 |
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Yohey, Terai : Department of Biosystems Science, The Graduate University for Advanced Studies (Sokendai) *(Assistant Professor) |
| 抄録 |
|
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内容記述タイプ |
Abstract |
|
内容記述 |
When a population size is reduced, genetic drift may fix slightly deleterious mutations, and an increase in nonsynonymous substitution is expected. It has been suggested that past aridity has seriously affected and decreased the populations of cichlid fishes in Lake Victoria, while geographical studies have shown that the water levels in Lake Tanganyika and Lake Malawi have remained fairly constant. The comparably stable environments in the latter two lakes might have kept the populations of cichlid fishes large enough to remove slightly deleterious mutations. The difference in the stability of cichlid fish population sizes between Lake Victoria and the Lakes Tanganyika and Malawi is expected to have caused differences in the nonsynonymous/synonymous ratio, ω (=dN/dS), of the evolutionary rate. Here, we estimated ω and compared it between the cichlids of the three lakes for 13 mitochondrial protein-coding genes using maximum likelihood methods. We found that the lineages of the cichlids in Lake Victoria had a significantly higher ω for several mitochondrial loci. Moreover, positive selection was indicated for several codons in the mtDNA of the Lake Victoria cichlid lineage. Our results indicate that both adaptive and slightly deleterious molecular evolution has taken place in the Lake Victoria cichlids' mtDNA genes, whose nonsynonymous sites are generally conserved. |
| 論文注記 |
|
|
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Available online 18 September 2014 |
| 書誌情報 |
Gene
en : Gene
巻 552,
号 2,
p. 239-245,
発行日 2014-12-01
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| 雑誌情報 |
|
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Vol. 1, no. 1 (1976)- |
| 雑誌情報 |
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Frequency : Biweekly |
| 出版者 |
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出版者 |
Elsevier/North-Holland Biomedical Press / Amsterdam |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0378-1119 |
| 書誌レコードID (NCID) |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11529840 |
| 書誌レコードID (NCID) |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00654385 |
| PubMed番号 |
|
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|
識別子タイプ |
PMID |
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関連識別子 |
25241383 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
http://dx.doi.org/10.1016/j.gene.2014.09.039 |
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関連名称 |
10.1016/j.gene.2014.09.039 ＜ScienceDirect Abstract＞ |
| 権利 |
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|
権利情報 |
© 2014 Elsevier B.V. All rights reserved. |
| 関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
http://www.sciencedirect.com/science/journal/03781119 |
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関連名称 |
Gene ＜Elsevier ScienceDirect＞ |
