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  1. 010 学術雑誌論文
  2. 大田, 竜也 / OTA, Tatsuya

A tetrapod-like repertoire of innate immune receptors and effectors for coelacanths.

https://ir.soken.ac.jp/records/5433
https://ir.soken.ac.jp/records/5433
a95f30fb-dc09-4e0a-ae8a-83d88589b870
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-02-23
タイトル
タイトル A tetrapod-like repertoire of innate immune receptors and effectors for coelacanths.
タイトル
タイトル A tetrapod-like repertoire of innate immune receptors and effectors for coelacanths.
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Animals
キーワード
言語 en
主題Scheme Other
主題 Carrier Proteins
キーワード
言語 en
主題Scheme Other
主題 Fishes
キーワード
言語 en
主題Scheme Other
主題 Immunity.Innate
キーワード
言語 en
主題Scheme Other
主題 Multigene Family
キーワード
言語 en
主題Scheme Other
主題 Phylogeny
キーワード
言語 en
主題Scheme Other
主題 Proteins
キーワード
言語 en
主題Scheme Other
主題 Receptors Pattern Recognition
キーワード
言語 en
主題Scheme Other
主題 Toll-Like Receptors <NML MeSH Terms>
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 BOUDINOT, Pierre

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BOUDINOT, Pierre

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ZOU, Jun

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ZOU, Jun

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OTA, Tatsuya

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OTA, Tatsuya

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BUONOCORE, Francesco

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BUONOCORE, Francesco

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SCAPIGLIATI, Giuseppe

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SCAPIGLIATI, Giuseppe

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CANAPA, Adriana

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CANAPA, Adriana

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CANNON, John

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CANNON, John

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LITMAN, Gary

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LITMAN, Gary

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HANSEN, John D

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HANSEN, John D

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著者別名 BOUDINOT, Pierre

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BOUDINOT, Pierre

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ZOU, Jun

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ZOU, Jun

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OTA, Tatsuya

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OTA, Tatsuya

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BUONOCORE, Francesco

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BUONOCORE, Francesco

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SCAPIGLIATI, Giuseppe

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SCAPIGLIATI, Giuseppe

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CANAPA, Adriana

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CANAPA, Adriana

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CANNON, John

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CANNON, John

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LITMAN, Gary

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LITMAN, Gary

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HANSEN, John D

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HANSEN, John D

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著者注記
Tatsuya, Ota:Department of Evolutionary Studies of Biosystems, The Graduate University for Advanced Studies *(Associate Professor)
抄録
内容記述タイプ Abstract
内容記述 The recent availability of both robust transcriptome and genome resources for coelacanth (Latimeria chalumnae) has led to unique discoveries for coelacanth immunity such as the lack of IgM, a central component of adaptive immunity. This study was designed to more precisely address the origins and evolution of gene families involved in the initial recognition and response to microbial pathogens, which effect innate immunity. Several multigene families involved in innate immunity are addressed, including: Toll-like receptors (TLRs), retinoic acid inducible gene 1 (RIG1)-like receptors (RLRs), the nucleotide-binding domain and leucine-rich repeat containing proteins (NLRs), diverse immunoglobulin domain-containing proteins (DICP) and modular domain immune-type receptors (MDIRs). Our analyses also include the tripartite motif-containing proteins (TRIM), which are involved in pathogen recognition as well as the positive regulation of antiviral immunity. Finally, this study addressed some of the downstream effectors of the antimicrobial response including IL-1 family members, type I and II interferons (IFN) and IFN-stimulated effectors (ISGs). Collectively, the genes and gene families in coelacanth that effect innate immune functions share characteristics both in content, structure and arrangement with those found in tetrapods but not in teleosts. The findings support the sister group relationship of coelacanth fish with tetrapods.
論文注記
Version of record online : 30 JAN 2014
書誌情報 Journal of experimental zoology. Part B, Molecular and developmental evolution (Special Issue: Genome of the African Coelacanth)
en : Journal of experimental zoology. Part B, Molecular and developmental evolution (Special Issue: Genome of the African Coelacanth)

巻 322, 号 6, p. 415-437, 発行日 2014-09
雑誌情報
Publication Start Year : 2003
雑誌情報
Frequency : Eight no. a year, 2008-
出版者
出版者 Wiley-Liss / Hoboken, NJ c2003-
ISSN
収録物識別子タイプ ISSN
収録物識別子 1552-5007
Online ISSN
収録物識別子タイプ ISSN
収録物識別子 1552-5015
書誌レコードID (NCID)
収録物識別子タイプ NCID
収録物識別子 AA1210851X
PubMed番号
識別子タイプ PMID
関連識別子 24482296
DOI
識別子タイプ DOI
関連識別子 http://dx.doi.org/10.1002/jez.b.22559
関連名称 10.1002/jez.b.22559 <Wiley Online Library>
権利
権利情報 © 2014 Wiley Periodicals, Inc.
関連サイト
識別子タイプ URI
関連識別子 http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1552-5015
関連名称 About Journal of Experimental Zoology Part B : Molecular and Developmental Evolution <Wiley Online Library>
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