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Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae.
https://ir.soken.ac.jp/records/5635
https://ir.soken.ac.jp/records/563573f6c126-66dc-43c5-bdaa-a219c73185f5
| 名前 / ファイル | ライセンス | アクション |
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本文 / Article (6.1 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-07-19 | |||||
| タイトル | ||||||
| タイトル | Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae. | |||||
| タイトル | ||||||
| タイトル | Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae. | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
SAITO, Shigeru
× SAITO, Shigeru× HAMANAKA, Gen× KAWAI, Narudo× FURUKAWA, Ryohei× GOJOBORI, Jun× TOMINAGA, Makoto× KANEKO, Hiroyuki× SATTA, Yoko |
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| 著者別名 |
SAITO, Shigeru
× SAITO, Shigeru× HAMANAKA, Gen× KAWAI, Narudo× FURUKAWA, Ryohei× GOJOBORI, Jun× TOMINAGA, Makoto× KANEKO, Hiroyuki× SATTA, Yoko |
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| 著者注記 | ||||||
| 値 | Jun, Gojobori：Department of Evolutionary Studies of Biosystems, School of Advanced Sciences, SOKENDAI (The Graduate University for Advanced Studies) *(Lecturer) | |||||
| 著者注記 | ||||||
| 値 | Yoko, Satta：Department of Evolutionary Studies of Biosystems, School of Advanced Sciences, SOKENDAI (The Graduate University for Advanced Studies) *(Professor) | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The vast majority of marine invertebrates spend their larval period as pelagic plankton and are exposed to various environmental cues. Here we investigated the thermotaxis behaviors of the bipinnaria larvae of the starfish, Patiria pectinifera, in association with TRPA ion channels that serve as thermal receptors in various animal species. Using a newly developed thermotaxis assay system, we observed that P. pectinifera larvae displayed positive thermotaxis toward high temperatures, including toward temperatures high enough to cause death. In parallel, we identified two TRPA genes, termed PpTRPA1 and PpTRPA basal, from this species. We examined the phylogenetic position, spatial expression, and channel properties of each PpTRPA. Our results revealed the following: (1) The two genes diverged early in animal evolution; (2) PpTRPA1 and PpTRPA basal are expressed in the ciliary band and posterior digestive tract of the larval body, respectively; and (3) PpTRPA1 is activated by heat stimulation as well as by known TRPA1 agonists. Moreover, knockdown and rescue experiments demonstrated that PpTRPA1 is involved in positive thermotaxis in P. pectinifera larvae. This is the first report to reveal that TRPA1 channels regulate the behavioral response of a marine invertebrate to temperature changes during its planktonic larval period. | |||||
| 論文注記 | ||||||
| 値 | Published online:19 May 2017 | |||||
| 書誌情報 |
Scientific reports en : Scientific reports 巻 7, 号 1, p. Article number: 2173 (2017), 発行日 2017-05-19 |
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| 雑誌情報 | ||||||
| 値 | Publication Start Year : 2011 | |||||
| 雑誌情報 | ||||||
| 値 | Frequency : Continuously updated | |||||
| 雑誌情報 | ||||||
| 値 | Scientific Reports is an online, open access journal from the publishers of Nature. | |||||
| 出版者 | ||||||
| 出版者 | Nature Publishing Group / London | |||||
| Online ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2045-2322 | |||||
| PubMed番号 | ||||||
| 表示名 | 28526851 | |||||
| URL | https://www.ncbi.nlm.nih.gov/pubmed/?term=28526851 | |||||
| PMC番号 | ||||||
| 表示名 | PMC5438368 | |||||
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438368/ | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | http://dx.doi.org/10.1038/s41598-017-02171-8 | |||||
| 関連名称 | 10.1038/s41598-017-02171-8 ＜Springer Nature Open Access Article＞ | |||||
| 権利 | ||||||
| 権利情報 | © The Author(s) 2017 | http://www.nature.com/srep/about/open-access | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.nature.com/srep/about | |||||
| 関連名称 | About Scientific reports ＜Springer Nature＞ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
