{"_buckets": {"deposit": "4c0b8da7-ede1-4761-8ae1-ef0081a22853"}, "_deposit": {"created_by": 24, "id": "5645", "owners": [24], "pid": {"revision_id": 0, "type": "depid", "value": "5645"}, "status": "published"}, "_oai": {"id": "oai:ir.soken.ac.jp:00005645", "sets": ["34"]}, "author_link": ["8187", "8186"], "item_2_creator_3": {"attribute_name": "著者名(英)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "KATSURA, Yukako", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "8187", "nameIdentifierScheme": "WEKO"}]}]}, "item_2_date_4": {"attribute_name": "発行日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2014-06-23", "subitem_date_issued_type": "Created"}]}, "item_2_description_13": {"attribute_name": "研究課題番号", "attribute_value_mlt": [{"subitem_description": "24770225", "subitem_description_type": "Other"}]}, "item_2_description_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_2_description_16": {"attribute_name": "研究期間", "attribute_value_mlt": [{"subitem_description": "2012～2013", "subitem_description_type": "Other"}]}, "item_2_description_17": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "研究成果の概要（和文）:\n本研究では、有袋類のオスがどのように遺伝的に決められるのかについて明らかにすることを目的として、これまで有袋類でのオス決定遺伝子SRYの進化・機能、オス精巣で発現する遺伝子の網羅的同定等を行ってきた。本研究の成果から、有袋類（ワラビー、コアラ等）SRYの配列は真獣類（ヒト、マウス等）のものと異なるが、有袋類SRYの機能は真獣類のものと類似していることが示唆された。以上の結果成果から、有袋類の性決定遺伝子は、SRYである可能性が高いことが示唆された。\n研究成果の概要（英文）:\nTo understand how marsupial male can be genetically determined, we have investigated molecular evolution and function of male determining gene SRY, and identified testis-expressed genes in marsupials by transcriptome analyses. Based on the molecular evolutionary and biochemical analyses, marsupial (wallabies, koalas and so on) SRY sequences are not conserved well compared to eutherian (humans, mice and so on) SRY, but the function of marsupial SRY is similar to eutherians. 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